...Lili Qin; Yanxia Wang; Yingying Liang; Qiang Li; Xuerong Xie; Honglian Zhang Introduction: Atorvastatin (ATO) is often used to reduce blood lipids and prevent atherosclerosis, but excessive use of ATO will lead to hepatotoxicity. This paper investigated the effects of astragaloside IV (AS IV...

...ZhengHu Xu; Wei Liu; Huai Huang Astragaloside IV (AS-IV) is an active component extracted from the traditional Chinese herbal medicine. AS-IV is a neuroprotective component in cerebral ischemic models. However, roles of AS-IV in cerebral ischemia-reperfusion (I/R) injury and the underlying...

...Biwang Liu; Huan Zhao; Yonghui Wang; Huizhong Zhang; Yanmiao Ma Background: Astragaloside IV has shown its promising effect on acute respiratory distress syndrome (ARDS). Objectives: We aim to explore whether astragaloside IV is effective for ARDS treatment in a lipopolysaccharides (LPS)-induced...

...Yu-Ying Qiu; Jin-Xiao Zhu; Tao Bian; Fei Gao; Xiu-Feng Qian; Qiang Du; Min-Yu Yuan; Hua Sun; Ling-Zhi Shi; Ming-Hong Yu Bronchial asthma is characterized by chronic lung inflammation, airway hyperresponsiveness, and airway remodelling. Astragaloside IV (3-O-β- D -xylopyranosyl-6-O-β- D...

...Da-Wei Zhang; Zhi-Ping Bian; Jin-Dan Xu; Heng-Fang Wu; Chun-Rong Gu; Bin Zhou; Xiang-Jian Chen; Di Yang Background: Astragaloside IV (As-IV) exerts beneficial effects on hypoxia/reoxygenation (H/R)-induced cardiomyocyte injury, possibly through normalization of sarcoplasmic reticulum Ca 2+ ATPase...

...Xiao-Le Xu; Xiang-Jian Chen; Hui Ji; Ping Li; Yun-Yun Bian; Di Yang; Jin-Dan Xu; Zhi-Ping Bian; Ji-Nan Zhang Although astragaloside IV, a saponin isolated from Astragalus membranaceus , has been shown to protect the myocardium against ischemia/reperfusion injury, its effect on the status...