...Zhe Wang; Yun Gong; Da-li Zeng; Lian-guo Chen; Gao-tong Lin; Cheng-ke Huang; Wei Sun; Meng-Chun Chen; Guo-xin Hu; Rui-jie Chen Background: CYP2C9 is one of the most important phase I drug-metabolizing enzymes in liver. The objective of this work was to investigate the effects of apigenin...

...Yun-yun Zhan; Bing-qing Liang; Er-min Gu; Xiao-xia Hu; Dan Lin; Guo-xin Hu; Zhi-qiang Zheng Objective: This study was conducted to investigate the effects of orally administered apigenin on the pharmacokinetics of venlafaxine (VEN) in rats and on the metabolism of VEN in human and rat liver...

...Kamel Gharzouli; Peter Holzer Flavonoids are known to relax precontracted intestinal smooth muscle and to delay intestinal transit. We therefore investigated the effects of quercetin, naringenin, apigenin and genistein on intestinal peristalsis in vitro. Peristalsis in fluid-perfused segments...