... the laxatives currently used may lead to morphologic changes of the autonomous nervous system of the colon. Melanosis coli is due to pigment-laden macrophages within the submucosa. It occurs after long-term intake of anthraquinones and has no functional consequences. No case of ‘cathartic colon’ has been...

...Karl Egil Malterud; Tove Lynn Farbrot; Anne Elisabeth Huse; Reidar Bredo Sund The activity of seven anthraquinones and four anthrones against nonenzymatic and enzymatic lipid peroxidation in vitro and their ability to scavenge free radicals have been studied. In nonenzymatic peroxidation in rat...

.... Rhein anthrone Peristaltic reflex Guinea pig isolated ileum Prostaglandins Cathartics Anthraquinones Gastrointestinal motility Pharmacology 1993;47(suppl l):40-48 Geert Nijsa Peter de Wittea Karel Geboesb Ann Meulemansc Jan Schuurkesc Joseph Lem lia a Laboratory of Pharmaceutical Biology...

... Anthraquinones Genotoxicity Evaluation of genotoxicity data Pharmacology 1993;47(suppl 1): 178-186 A. Heidemanna II. G. Miltenburgerb U. Mengsc CCR Cytotcst Cell Research. Rossdorf; LMP. Laboratorium fur Mutagenitätsprüfung, Technische Hochschule Darmstadt; Abteilung Toxikologie, Madaus AG, Köln, FRG...

... to in the content or advertisements. Laxatives Anthraquinones Sennosides Rhein Bisacodyl Large intestine Transit time Absorption Rat Pharmacology 1989;38:310-318 © 1989 S. Karger AG, Basel 0031 -7012/89/0385-0310S2.75/0 Effects of Sennosides A + B and Bisacodyl on Rat Large Intestine Elke Leng...

... such experiments on anthraquinone diphenols are lacking. Everted sacs of rat jejunum and stripped colon were filled with Krebs-Henseleit solution (K-H) on the serosal (BL) side, and bathed at the mucosal (LU) side with K-H containing either danthron (3–4 nmol/ml) or rhein (10 nmol/ml). After 60 min incubation...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Anthraquinones Sennosides Danthron Toxicity Intestine Electron microscopy Rat Pharmacology 36: suppl. 1, pp. 194-202 (1988) © 1988 S. Karger AG. Basel 0031-7012/88/0367-0194S2.75/0 Long-Term...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Laxatives Anthraquinones Sennosides Intestine Rat Electron microscopy Pharmacology 36: suppl. I, pp. 188-193 (1988) © 1988 S. Karger AG. Basel 0031-7 0 12/88/0367-0188S2.75/0 Electron...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Laxatives Anthraquinones Sennosides Toxicity, acute, subacute and chronic Reproduction Mutagenicity Toxicology...