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Keywords: Adriamycin nephropathy
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Journal Articles

Epigallocatechin-3-Gallate Attenuates Adriamycin-Induced Focal Segmental Glomerulosclerosis via Suppression of Oxidant Stress and Apoptosis by Targeting Hypoxia-Inducible Factor-1α/ Angiopoietin-Like 4 Pathway

Subject Area:
Pharmacology
Guoyong Liu, Liyu He
Journal: Pharmacology
Pharmacology (2019) 103 (5-6): 303–314.
https://doi.org/10.1159/000496799
Published Online: 06 March 2019
...: In C57BL/6 mice, Adriamycin nephropathy (AN) was induced by Adriamycin (10 mg/kg body weight, diluted in normal saline) via a tail vein on day 0. Then the mice were given with EGCG (20 mg/kg body weight) or YC-1 (Lificiguat, a specific inhibitor of hypoxia-inducible factor-1α [HIF-1α], 50 mg/kg body weight...
View articletitled, Epigallocatechin-3-Gallate Attenuates Adriamycin-Induced Focal Segmental Glomerulosclerosis via Suppression of Oxidant Stress and Apoptosis by Targeting Hypoxia-Inducible Factor-1α/ Angiopoietin-Like 4 Pathway
Open the PDF for Epigallocatechin-3-Gallate Attenuates Adriamycin-Induced Focal Segmental Glomerulosclerosis via Suppression of Oxidant Stress and Apoptosis by Targeting Hypoxia-Inducible Factor-1α/ Angiopoietin-Like 4 Pathway in another window
Journal Articles

Resveratrol Attenuates Adriamycin-Induced Focal Segmental Glomerulosclerosis through C3aR/C5aR- Sphingosine Kinase 1 Pathway

Subject Area:
Pharmacology
Guoyong Liu, Qiang Wang, Yan Shi, Xiaofei Peng, Hong Liu, Youming Peng, Liyu He
Journal: Pharmacology
Pharmacology (2017) 100 (5-6): 253–260.
https://doi.org/10.1159/000479525
Published Online: 11 August 2017
... compound, which has been reported to suppress inflammatory response and renal interstitial fibrosis. This study is aimed at evaluating the renoprotective effect of RSV treatment on adriamycin-induced FSGS. Methods: In Balb/c mice, adriamycin nephropathy was induced by adriamycin (10 mg/kg body weight...
View articletitled, Resveratrol Attenuates Adriamycin-Induced Focal Segmental Glomerulosclerosis through C3aR/C5aR- Sphingosine Kinase 1 Pathway
Open the PDF for Resveratrol Attenuates Adriamycin-Induced Focal Segmental Glomerulosclerosis through C3aR/C5aR- Sphingosine Kinase 1 Pathway in another window
Journal Articles

Astaxanthin Attenuates Adriamycin-Induced Focal Segmental Glomerulosclerosis

Subject Area:
Pharmacology
Guoyong Liu, Yan Shi, Xiaofei Peng, Hong Liu, Youming Peng, Liyu He
Journal: Pharmacology
Pharmacology (2015) 95 (3-4): 193–200.
https://doi.org/10.1159/000381314
Published Online: 22 April 2015
... and oxidative stress. Astaxanthin (ATX) has a broad range of biological functions, particularly antioxidant and anti-inflammatory ones. This study was designed to evaluate the renoprotective effect of ATX treatment on Adriamycin-induced FSGS. Methods: In Balb/c mice, Adriamycin nephropathy was induced...
View articletitled, Astaxanthin Attenuates Adriamycin-Induced Focal Segmental Glomerulosclerosis
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