...David Naguib; Carolin Helten; Saif Zako; Philipp Mourikis; René M’Pembele; Kajetan Trojovsky; Samantha Ahlbrecht; Dorothee Zikeli; Tobias Zeus; Malte Kelm; Lisa Dannenberg; Amin Polzin Additional loading dose of acetylsalicylic acid (ASA) during percutaneous coronary interventions (PCIs) despite...

...Katja Anger; Jörg Kempfert; Martin Kostelka; Friedrich-Wilhelm Mohr; Stefan Dhein In the present study, we investigated prospectively whether an existing platelet hyporesponsiveness to acetylsalicylic acid (ASA) can be transferred to platelets with a previously normal reactivity to ASA. Therefore...

...Martijn G.H. van Oijen; Christine Barthélémy; Marcel J.R. Janssen; Etienne Joiris; Wilbert H.M. Peters; Robert J.F. Laheij; Paul Smits; Pascal Odou; Jan B.M.J. Jansen Objective: To compare plasma concentrations of acetylsalicylic acid (ASA) and its metabolites between genetic polymorphisms...

..., to have a variety of effects on cartilage repair processes in diseased articular cartilage. The aim of this study was to ascertain the effects of meloxicam on some of these processes using in vitro models. Acetylsalicylic acid, a NSAID whose characteristics have been previously elucidated in the models...

...L.-A. Pini; G. Vitale; M. Sandrini Acetylsalicylic acid (ASA), 400 mg/kg i.p., displayed antinociceptive activity in both the hot-plate and the formalin test. ASA significantly increased brain serotonin (5-HT) content and reduced the number of 5-HT 2 receptors in cortical brain membranes 30 min...

...Pérez Vallina; B. Cantabrana; A. Hidalgo The effects of the nonsteroidal anti-inflammatory drugs (NSAIDs) acetylsalicylic acid, metamizole, phenylbutazone, indometacin, piroxicam, naproxen, tolmetin, diclofenac, and mefenamic acid on methacholine (10 µmol/l), prostaglandin F 2α (1 µmol/l), and KCl...

...Z. Sevim Ercan; Sami Eren; Hakan Zengil; R. Kazim Türker α-Naphthylthiourea (ANTU) when injected intraperitoneally to rats at a dose of 10 mg/kg elicited lung oedema indicated by an increase in lung weight/body weight (LW/BW) ratio and pleural effusion. The injection of acetylsalicylic acid, which...

... of salicylamide in the combinations was demonstrated by this method. None of the investigated combination products was superior to the same doses of either acetylsalicylic acid, paracetamol or phenazone. 5 02 1982 10 05 1982 4 6 2008 © 1982 S. Karger AG, Basel 1982 Copyright / Drug Dosage...

...U. Weissenborn; S. Maedge; K.-Fr. Sewing The effect of 16, 16-dimethyl prostaglandin E 2 (DmPGE 2 ), in doses subthreshold for antisecretory activity, were examined in female rats. The aims were to determine if DmPGE 2 alters the disposition of acetylsalicylic acid (ASA) within the gastric mucosa...

... the administration of certain anti-inflammatory agents such as acetylsalicylic acid. Radiography and in particular exact histological examination of the knee joints revealed, however, that neither the overall incidence nor the severity of osteoarthrosis was greater in the mice treated with C 21 524-Su than...

... of acetylsalicylic acid was ulcerogenic and caused fecal blood loss in the fasted rat. Neither substance caused mortalities at the doses tested. Pharmacology 17: 79 82 (1978) Effect of Aq-Tetrahydrocannabinol on the Gastrointestinal Tract of the Rat R. Duane Sofia, William Diamantis and Jerome Edelson Department...

...H.-H. Frey In order to elucidate the mechanism of the acetylsalicylic acid-induced bronchoconstrictor responses which have been observed in asthmatic patients, experiments were done in cats, anesthetized by chloralose, vagotomized, and completely relaxed by infusion of suxamethonium. In about half...

...G. Wilhelmi; R. Menassé-Gdynia Experiments in rats of different ages have shown that juvenile animals are less sensitive than adults to the gastric irritant effects of non-steroid anti-inflammatory drugs, such as acetylsalicylic acid, oxyphenbutazone and phenylbutazone, although the anti-oedematous...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Absorption Acetylsalicylic acid Aspirin Excretion Phenacetin Salicylates...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Acetylsalicylic acid Analgesic drugs Anti-inflammatory drugs Imidazole Pharmacology 10: 161-168(1973) Pharmacological Properties of Imidazole I. Analgesic and Anti-Inflammatory Actions P. Puig...

..., in comparison with a standard thromboxane synthase inhibitor (dazoxiben) and a cyclooxygenase inhibitor (acetylsalicylic acid). With respect to platelet aggregation in whole blood, the 50% inhibitory concentrations (IC 50 ) of camonagrel were between 318 and 797 µmol/l after induction with collagen...

...Maurizio Sandrini; Giovanni Vitale; Luigi Alberto Pini Male Wistar rats were treated with ondansetron (1 and 2 mg/kg s.c.), ketanserin (0.2, 1 and 5 mg/kg s.c.) or NAN-190 (1, 3 and 5 mg/kg i.p.) 15 min before acetylsalicylic acid (ASA, 400 mg/kg i.p.), and 30 min thereafter the pain threshold...