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Keywords: ATP-binding cassette transporter A1
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Journal Articles

Ezetimibe-Mediated Protection of Vascular Smooth Muscle Cells from Cholesterol Accumulation through the Regulation of Lipid Metabolism-Related Gene Expression

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Subject Area:
Pharmacology
Yong-Zhen Gong, Shao-Wei Sun, Hao-Yu Yuan, Xue-Jiao Xie, Qin-Hui Tuo, Xue-Feng Yang, Xi Tan, Xi-Long Zheng, Yan Xiong, Duan-Fang Liao
Journal: Pharmacology
Pharmacology (2015) 94 (5-6): 214–222.
https://doi.org/10.1159/000368803
Published Online: 11 November 2014
...-regulatory element binding protein 1 ATP-binding cassette transporter A1 Caveolin-1 Atherosclerosis-related disorders are the leading cause of death in cardiovascular disease [ 1 ]. The abnormal metabolism and elevation of plasma cholesterol and lipoproteins are well-documented risk factors...
View articletitled, Ezetimibe-Mediated Protection of Vascular Smooth Muscle Cells from Cholesterol Accumulation through the Regulation of Lipid Metabolism-Related Gene Expression
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Journal Articles

Aspirin Increases Apolipoprotein-A-I-Mediated Cholesterol Efflux via Enhancing Expression of ATP-Binding Cassette Transporter A1

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Subject Area:
Pharmacology
Yu-Hua Wang, Yan-Fang Chen, Shao-Rui Chen, Xi Chen, Jian-Wen Chen, Xiao-Yan Shen, Yong-gao Mou, Pei-Qing Liu
Journal: Pharmacology
Pharmacology (2010) 86 (5-6): 320–326.
https://doi.org/10.1159/000321727
Published Online: 19 November 2010
...Yu-Hua Wang; Yan-Fang Chen; Shao-Rui Chen; Xi Chen; Jian-Wen Chen; Xiao-Yan Shen; Yong-gao Mou; Pei-Qing Liu Background: The efflux of cellular cholesterol mediated by apolipoprotein (apo)A-I and ATP-binding cassette transporter A1 (ABCA1) is a major pathway of reverse cholesterol transport. We...
View articletitled, Aspirin Increases Apolipoprotein-A-I-Mediated Cholesterol Efflux via Enhancing Expression of ATP-Binding Cassette Transporter A1
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Journal Articles

Liver X Receptor Agonist Methyl-3β-Hydroxy-5α,6α-Epoxycholanate Attenuates Atherosclerosis in Apolipoprotein E Knockout Mice without Increasing Plasma Triglyceride

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Subject Area:
Pharmacology
Wei Yan, Tongxin Zhang, Jun Cheng, Xiangdong Zhou, Xiaolong Qu, Houyuan Hu
Journal: Pharmacology
Pharmacology (2010) 86 (5-6): 306–312.
https://doi.org/10.1159/000321320
Published Online: 11 November 2010
... in mice and to increase the expression of ATP-binding cassette transporter A1 (ABCA1) in the atherosclerotic lesions. However, these compounds increase plasma and hepatic triglyceride (TG) levels in mice. Methyl-3β-hydroxy-5α,6α-epoxycholanate (MHEC), synthesized from hyodeoxycholic acid, functions...
View articletitled, Liver X Receptor Agonist Methyl-3β-Hydroxy-5α,6α-Epoxycholanate Attenuates Atherosclerosis in Apolipoprotein E Knockout Mice without Increasing Plasma Triglyceride
Open the PDF for Liver X Receptor Agonist Methyl-3β-Hydroxy-5α,6α-Epoxycholanate Attenuates Atherosclerosis in Apolipoprotein E Knockout Mice without Increasing Plasma Triglyceride in another window