...Miseon Lee; Tae-im Kim; Se Jin Jang; Kyung-Ja Cho; Sang Min Lee; Hyeong Ryul Kim; Joon Seon Song Introduction: Pleuropulmonary blastoma (PPB) is a rare sarcomatous malignancy involving the lung and pleura which occurs in early childhood. Cystic PPB in the early stage can be misdiagnosed as other...

...Diana Martins; Fernando Mendes; Fernando Schmitt Lung cancer is still the leading cause of cancer death worldwide. Despite the major diagnostic and therapeutic innovations, the effect on mortality has been modest and the overall survival is still poor. Better understanding of the pathology...

... role in pathophysiology remains unclear. We investigated the subcellular localization of cortical actin by the histopathological and experimental studies of lung adenocarcinomas. Materials and Methods: The subcellular localization of cortical actin was studied in surgically resected lung...

...Hyun-Soo Kim; Gou Young Kim; Sung-Jig Lim; Youn Wha Kim Objective: We investigated whether the expression of mammalian target of rapamycin (mTOR) pathway components is associated with clinicopathologic characteristics and patient outcome in lung adenocarcinoma (AC) and squamous cell carcinoma (SCC...

... have been identified in vertebrates and all share a cysteine-rich region. However, the physiological function(s) of the individual Sprouty homologs is unknown. mRNA of Sprouty homologs is expressed during mouse lung development. In the present study, we investigated the immunolocalization of Sprouty...

... and participate in migration, matrix degradation and invasion. We investigated an alteration of subcellular localization of invadopodia-related actin-associated proteins, actinin-1 and cortactin, in lung adenocarcinomas, its clinical significance, and its possible regulatory factors. Methods: Invadopodia-related...

... in small vessels but also in larger vessels. In contrast to normal control, lung tissue from the asthma model showed dual expression for CD31 and von Willebrand factor in the endothelial cells and α-smooth muscle actin and desmin in the mural cells of the vessels, suggesting a phenotypic and functional...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Asthma model Eosinophils Inflammation Lung Periarterial space Ultrastructure 31 3 2006 Original Paper Pathobiology 2005;72:308 315...

...Takumi Akashi; Junko Minami; Yuki Ishige; Yoshinobu Eishi; Touichiro Takizawa; Morio Koike; Masaki Yanagishita Objective: Proliferation of fibroblasts (desmoplastic reaction) in the lung adenocarcinomas is an important phenomenon that correlates with metastases and poor prognosis. Because basement...

...R. Pabst In mammal lungs different compartments for leukocytes can be identified during health and disease, e.g. lung interstitium, bronchoalveolar space, the epithelium and lamina propria of the air-conducting part. A so far neglected compartment is the space around the branches of the pulmonary...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cytokine Allergy Inflammation Lung Transcription Pathobiology 2002 03;70:293 296 DOI: 10.1159/000070745...

...Annette M. Müller; Maya Nesslinger; Guido Skipka; Klaus-Michael Müller Objectives: The morphological phenotype of endothelial cells (EC) is specific for individual types of vessels. There are, however, no studies on the phenotypical diversity of EC in human lung tissue. The influences exerted...