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Keywords: Hutchinson-Gilford progeria syndrome
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Journal Articles

Restoring SIRT6 Expression in Hutchinson-Gilford Progeria Syndrome Cells Impedes Premature Senescence and Formation of Dysmorphic Nuclei

Subject Area:
Further Areas , Oncology , Pathology and Cell Biology
Helal Endisha, Jacqueline Merrill-Schools, Min Zhao, Molly Bristol, Xu Wang, Nard Kubben, Lynne W. Elmore
Journal: Pathobiology
Pathobiology (2015) 82 (1): 9–20.
https://doi.org/10.1159/000368856
Published Online: 28 February 2015
...Helal Endisha; Jacqueline Merrill-Schools; Min Zhao; Molly Bristol; Xu Wang; Nard Kubben; Lynne W. Elmore Objectives: Mice overexpressing SIRT6 live longer than wild-type mice while SIRT6 knockout mice exhibit similar degenerative phenotypes as individuals with Hutchinson-Gilford progeria syndrome...
View articletitled, Restoring SIRT6 Expression in Hutchinson-Gilford Progeria Syndrome Cells Impedes Premature Senescence and Formation of Dysmorphic Nuclei
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