... of Pathology. McGill University. Montreal. Que.. Canada Proteoglycan Synthesis by the IMeointimal Smooth Muscle Cells Cultured from Rabbit Aortic Explants following De-Endothelialization Key Words Proteoglycan synthesis Smooth muscle cells Neointima Arterial injury Glycosaminoglycans Atherosclerosis Abstract...

...Judith L. Godden; Michael Edward; Allison W. Grant; Rona M. MacKie Glycosaminoglycans (GAGs), and in particular hyaluronan, are known to play a role in tumour cell migration, invasion and metastasis. Conditioned medium from two human metastatic melanoma cell lines (Hs294T and C8161) shows potent...

... inhibits glycoprotein and glycosaminoglycan synthesis. The concentration of DON ranged from 5-100 µg/ml; the lowest dose at which consistent results were obtained was 75 µg/ml. At the end of a 4-day culture period, controls displayed characteristic incisiform or molariform morphologies and possessed...

..., instructions or products referred to in the content or advertisements. Retinoids Invasion Metastasis Cell adhesion Glycosaminoglycans Heparanase Collagenase 30 05 1991 4 06 1991 7 10 2008 Michael Edward Department of Dermatology, Anderson College Building, University...

... and early replacement of hyaluronic acid by sulfated glycosaminoglycans (GAGs) both in these arteries and in Wharton’s jelly. Such a remodelling of the umbilical cord tissues is accompanied by an increase in insulin-like growth factor-I (IGF-I) concentration in the umbilical cord serum. Methods: Contact...