... Lewis rats and incubated on slides coated with fibronectin (FN), laminin (LN), or collagen (COLL) types I, III and IV. In other experiments, DC were pre-incubated with selected proinflammatory cytokines (IL-1, IL-2, IFN-γ, TNF-α) in order to determine their abilities to modulate cell adherence to ECM...

... was intended as a model to study the mechanisms of endothelial regeneration. All components were coated onto sterile coverslips at a concentration of 10 µg/ml. The highest expansion was obtained on fibronectin, laminin and collagen type III, all three being statistically significantly greater than...

...Charleata A. Carter; Günter Vollmer; David G. Kaufman We utilized confocal laser scanning microscopy to examine the localization of fibronectin deposition in cultures of human endometrial stromal cells. We found that fibronectin in normal human endometrial stromal cell cultures was both...

...R. Rajaraman; K. Lonergan Several types of normal diploid cells, established ‘normal’ cells, and transformed cells of human and rodent origin have been studied with reference to cell surface fibronectin distribution and their anchorage-independent growth behavior. All cell types that showed...

...Koichi Hirata; Yutaka Yoshida; Koji Shiramatsu; Aaron E. Freeman; Hiroshi Hayasaka The effects on mouse liver cells of laminin, fibronectin and type IV collagen, all of which are the main matrix of the basement membrane, were studied. Laminin, a glycoprotein isolated from cultures of rat yolk sac...

...Guido Tarone; Maria Rosa Amedeo; Maria Flavia Di Renzo; Paolo Comoglio Five independent hybrids producing monoclonal antibodies to human plasma fibronectin have been obtained by fusing P3/X63-Ag8 myeloma cells with immune mouse splenocytes. The specificity of these monoclonal antibodies (MABs...

...Levy Kopelovich; Clifford Murray; Hynda K. Kleinman; George R. Martin; Yuh Fukuda; Stephen I. Rennard Cultured skin fibroblasts from patients with hereditary adenomatosis of the colon and rectum (ACR) have a disorganized cytoskeleton. Since fibronectin has been found to restore normal cytoskeletal...

...R. Silberberg; W. Meier-Ruge; B. Odermatt Fibronectin stains were carried out and evaluated by microspectrophotometric techniques in annuli fibrosi of vertebral discs of sand rats (Psammomys obesus) of both sexes and two age groups, 13–18 months and over 2 years of age. The distribution...

...R. Silberberg; W. Meier-Ruge; B. Odermati Annulus fibrosus of intervertebral discs from diabetic and non-diabetic sand rats were examined by microspectrophotometry for fibronectin content. This was higher in the diabetic animals both in the dorsal and ventral parts and in the outer and inner...

... myocarditis. The aim of this study was to determine the effect of human and rat IL-1 on the production of fibronectin (FN) by rat cardiac fibroblast cultures. Methods: To test the role of IL-1 in the production of ECM, we determined the FN content in supernatants of rat myocardial fibroblast cultures...

... of both fibronectin and type III collagen. Fibronectin was seen in both early and latter responses to infarction while type III collagen was seen mainly in areas of incomplete healing among myocytes and around intramyocardial branches of the coronary arteries. The long-term low-dosage administration...