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Keywords: CFTR
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Journal Articles
Journal:
Pathobiology
Pathobiology (2004) 71 (3): 152–158.
Published Online: 02 April 2004
...Donald J. Davidson; Sheila Webb; Peter Teague; John R. W. Govan; Julia R. Dorin Objective: To establish the role of defects in murine Cftr in the susceptibility to Staphylococcus aureus lung disease using mouse models of cystic fibrosis (CF), congenic or inbred strains. Methods: We describe...
Journal Articles
Residual cftr Expression Varies with Age in cftr tm1Hgu Cystic Fibrosis Mice: Impact on Morphology and Physiology
Available to PurchaseM. Larbig, S. Jansen, M. Dorsch, W. Bernhard, B. Bellmann, J.R. Dorin, D.J. Porteous, H. von der Hardt, I. Steinmetz, H.-J. Hedrich, B. Tuemmler, T. Tschernig
Journal:
Pathobiology
Pathobiology (2002) 70 (2): 89–97.
Published Online: 20 December 2002
... in most strains. In this work, the issue was addressed whether aging of the respiratory tract leads to lung pathophysiology in the exon 10 insertional mutant cftr tm1Hgu mouse. Weight gain, body weight and life-span of cftr tm1Hgu mice were significantly reduced compared with control mice. cftr tm1Hgu...