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Keywords: CD30 antigen
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Journal Articles

CD3+/CD30+ Circulating T Lymphocytes Are Markedly Increased in Older Subjectswith Down’s Syndrome (Tr isomy 21)

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Subject Area:
Further Areas , Oncology , Pathology and Cell Biology
A. Bertotto, S. Crupi, G.M. Fabietti, S. Troiani, C. Parente, D. Mezzetti, R. Vaccaro
Journal: Pathobiology
Pathobiology (1999) 67 (2): 108–110.
https://doi.org/10.1159/000028058
Published Online: 22 February 1999
... were dramatically enhanced in the circulation of older DS subjects. Since CD30 antigen expression is considered to be a marker of T-helper-2 (Th-2) activation, and Th-2+ cells are associated with certain human pathologies, our data may in some way explain the enhanced susceptibility of DS patients...
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