...Hang Dong; Guangyu Jiang; Jiayue Zhang; Yuming Kang Background: The dysregulation of proliferation and migration of vascular smooth muscle cells (VSMCs) is one of the major causes of atherosclerosis (AS). Accumulating studies confirm that Kruppel-like factor 4 (KLF4) can regulate the proliferation...

.... Dyslipidemia is associated with increased oxidative stress, diminished overall antioxidative protection and increased risk for atherosclerosis. Very recently increased cardiovascular biomarkers (in particular alterations of lipoprotein A and d-dimer concentrations) were observed in sarcoidosis patients, mainly...

... the relationship between mesenteric fat accumulation and insulin resistance, hyperlipidemia and atherosclerosis. Methods: Glucose tolerance tests were performed using adult (11- to 15-month-old) and middle-aged (17- to 21-month-old) WHHLMI rabbits fed standard chow restrictedly. In addition, lipoprotein lipid...

...Zhihe Li; Misbahuddin Z. Alavi; Fasahat Wasty; Zorina Galis; Sean Moore Proteoglycans (PGs), the essential component of the extracellular matrix, are implicated in the pathogenesis of atherosclerosis. In an experimental model of injury, PGs accumulate in the neointimal tissue parallel with lipid...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Endothelial cells Cholesterol Atherosclerosis 28 03 1993...

...Jianglin Fan; Tatsuro Shimokama; Osamu Tokunaga; Teruo Watanabe Intimal infiltration of lipid-filled macrophages (Mφs) is an important event in the pathogenesis of atherosclerosis. To better understand Mφ functions, a model for the extravascular in vivo generation of foam cells in rat peritoneal...

...Zoltan Szekanecz; Manisha R. Shah; Lisa A. Harlow; William H. Pearce; Alisa E. Koch Angiogenesis, the growth and proliferation of blood vessels, may be important in the pathogenesis of atherosclerosis and thus in human atherosclerotic abdominal aortic aneurysms (AAAs). Endothelial migration...

..., instructions or products referred to in the content or advertisements. Malondialdehyde Oxidized low density lipoproteins Complement activation Atherosclerosis Pathobiology Original Paper Palhobiology 1996;64:73-78 James M. Sorace Sandy Rollins Jacinta U. Aniagolu Wolfgang J. Mergner Katherine Cole...

...W.E. Stehbens The etiology of atherosclerosis must explain the development of primary pathological complications (intimal tears, ectasia, tortuosity, aneurysms and stenoses). They are interrelated and associated with destruction of mural architecture and concomitant loss of tensile strength...

... the functional alteration of ECs in diet-induced atherosclerosis, immunoreactive endothelin-1 (irET-1) release by ECs of the rabbit aorta was correlated with scanning electron microscopy. Rabbits were fed a cholesterol diet for 12 weeks: by scanning electron microscopy, the area of ECs in the aorta increased...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Low-density lipoprotein, normal Hypercholesterolemia Atherosclerosis Evaluation of LDL Hypercholesterolemia...

... of lipids in myocytes. Lipid-laden myocytes and ground substance mucopolysaccharides represent sinks in which lipids are removed from the flow and accumulate locally. 30 05 1990 24 09 1990 7 10 2008 Macrophages Atherosclerosis Gadolinium chloride Myocytes Macrophages...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Atherosclerosis Artery Intimal thickening Lipid deposition Permeability Proc. 12th Conf. Int. Soc. Geograph. Path., Zurich, September 1975 Path. Microbiol. 43: 129-133...

... and risk of rupture. Atherosclerosis Plaques Stroke Heart disease © 2008 S. Karger AG, Basel 2008 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Atherosclerosis CD105 CD31 Neovascularisation TGFβ 1 Original Paper Pathobiology 2006;73:192 197 DOI: 10.1159...

... treatment with allicin significantly inhibited both native LDL and oxidized LDL degradation by isolated mouse macrophages. Conclusions: By using a pure allicin preparation, we were able to show that allicin may affect atherosclerosis not only by acting as an antioxidant, but also by other mechanisms...

...-Lipoxygenase Oxidation Atherosclerosis Original Paper Pathobiology 2004;71:261 266 DOI: 10.1159/000080060 Received: October 6, 2003 Accepted: April 8, 2004 Overexpression of 15-Lipoxygenase in the Vascular Endothelium Is Associated with Increased Thymic Apoptosis in LDL Receptor-Deficient Mice A. Afeka N...

... expression in mouse aorta in a model for atherosclerosis. Methods: Gene expression profiles were investigated in plaque-prone and plaque-resistant localizations in the ascending aorta and arch in 8-week-old ApoE–/– and LDLR–/– mice. Total RNA was extracted and two rounds of subtraction were performed...

...A. Gonen; A. Shaish; A. Leikin-Frenkel; T. Gilat; D. Harats Objective: The aim of the current research was to study whether fatty acid bile acid conjugates (FABACs) have a beneficial effect on atherosclerosis progression and blood lipid levels in mice. Methods: C57BL/6 female mice, fed a high-fat...

... genes and markers for further studies into the pathogenesis of atherosclerosis. Methods: Cells of the monocytic cell line THP-1 were activated by PMA and exposed to oxidized low-density lipoprotein. Gene expression profiles were investigated after 24 h, using a solid phase cDNA representational...