...Wenhui Mo; Xuanfu Xu; Ling Xu; Feng Wang; Aiwu Ke; Xingpeng Wang; Chuanyong Guo Purpose: To investigate the effect and possible mechanisms of resveratrol on pancreatic cancer cells in vitro. Methods: After being treated with resveratrol, cell viability, cell cycle phase distribution and apoptosis...

... to possess anticancer properties. However, the relationship between ω3-PUFAs and β-catenin, one of the key components of the Wnt signaling pathway, in human pancreatic cancer remains poorly characterized. Methods: Human pancreatic cancer cells (SW1990 and PANC-1) were exposed to two ω3-PUFAs, docosahexaenoic...

... (RPMI-1640) conditioned by two human pancreatic cancer cell lines (Panc-1 and HPAF), a hamster pancreatic cancer cell line (PC-1), a human epidermoid carcinoma cell line (A-431), and a human fibroblastic cell line (Ag-1523). Non-conditioned RPMI-1640 medium was used as control. Results: Amino acid...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. FE-1 and QoL Pancreatic cancer Surgery Pancreatic exocrine insufficiency Coefficient of fat absorption Kausch...

...Asif Khalid; John Dewitt; N. Paul Ohori; Jey-Hsin Chen; Kenneth E. Fasanella; Michael Sanders; Kevin M. McGrath; Marina Nikiforova Background/Aims: Autoimmune pancreatitis (AIP) may mimic pancreatic cancer (PC). The detection of DNA mutations in endoscopic ultrasound-guided fine needle aspiration...

... pancreatobiliary diseases, and healthy controls. Conclusion: MIC-1 is a valuable tumor marker for the diagnosis of pancreatic cancer. It has a good correlation with CA 19-9. TPS has no diagnostic importance to differentiate pancreatobiliary diseases. When pancreatic and other periampullary carcinomas were...

..., instructions or products referred to in the content or advertisements. Pancreatogenic diabetes Hepatic insulin resistance Pancreatic polypeptide Pancreatic cancer Metformin Pancreatic exocrine insufficiency Pancreatogenic diabetes, due to pancreatic disease, injury or resection, ranges...

...Chen Sun; Ann H. Rosendahl; Roland Andersson; DeQuan Wu; Xiangdong Wang Background: Pancreatic cancer is a highly malignant cancer and the fourth leading cause of cancer-related death. It is characterized by a rapid disease progression, a highly invasive tumor phenotype, and frequently resistance...

...Koji Yamaguchi The clinical outcome of patients with pancreatic cancer remains dismal despite recent advances in diagnostic and therapeutic modalities. Several risk factors have been reported regarding the development of pancreatic cancer. These risk factors include family history, accompanying...

...Hiroki Sakamoto; Masayuki Kitano; Takamitsu Komaki; Hajime Imai; Ken Kamata; Masatoshi Kudo Abdominal pain in patients with pancreatic cancer is a common symptom that is often difficult to manage. Opioids are frequently used in an attempt to mitigate pain; however, side effects may develop. Celiac...

...Wei Wang; Zhuan Liao; Gang Li; Zhao-Shen Li; Jie Chen; Xian-Bao Zhan; Luo-Wei Wang; Feng Liu; Liang-Hao Hu; Yan Guo; Duo-Wu Zou; Zhen-Dong Jin Background and Aim: It is suggested that patients with chronic pancreatitis (CP) have a markedly increased risk of pancreatic cancer compared...

.../500 µ M ). Pancreatic cancer is the fourth and fifth most frequent cause of cancer mortality in men and women respectively in the US [ 1 ]. Estimated new pancreatic cancer cases and deaths in the US in 2005 are 32,160 and 31,800, respectively [ 2 ]. Surgery is an option in less than 1 of 5...

...Kenneth E. Fasanella; Alyssa Krasinskas; Karen E. Schoedel; Eizaburo Sasatomi; Adam Slivka; David C. Whitcomb; Michael Sanders; Laurentia Nodit; Stephen Raab; Kevin M. McGrath; N. Paul Ohori; Asif Khalid Background/Aims: Preoperative distinction between pancreatic cancer (PC) and extrahepatic...

...A. Bartosch-Härlid; R. Andersson Pancreatic cancer is strongly associated with the development of hyperglycemia, peripheral insulin resistance and diabetes mellitus, especially when presented as new-onset diabetes mellitus. Peripheral insulin resistance and hyperinsulinemia have been suggested...

...M. Oliverius; Z. Kala; M. Varga; R. Gürlich; V. Lanska; H. Kubesova Background: Improving life expectancy is associated with increasing incidence of pancreatic cancer. We reviewed morbidity and mortality in patients aged 65 years and older undergoing curative intent surgery in two centers...

... NFAT members is now recognized as an important aspect for oncogenic transformation in several human malignancies, most notably in pancreatic cancer. Sustained activation of the Ca 2+ /calcineurin/NFAT signaling pathway has emerged as a powerful regulatory principle governing pancreatic cancer cell...

... the presence of mucin in the MPD in all (100%) patients and the communication between the cyst and the MPD in 65 (38.7%) patients. Of the 168 BD-IPMN patients, 9 (5.4%) had PC. None of the 9 patients had a family history of pancreatic cancer. The clinical features of the PC-developing patients are summarized...

...Brenda Diergaarde; Randall Brand; Janette Lamb; Soo Yeon Cheong; Kim Stello; M. Michael Barmada; Eleanor Feingold; David C. Whitcomb Background/Aims: Knowledge regarding genetic factors that influence pancreatic cancer risk is currently limited. To identify novel pancreatic cancer susceptibility...

... secretory trypsin inhibitor (PSTI) ((HAT + HCT)/PSTI) are disturbed in patients with pancreatic cancer. The aim of this study was to investigate if pre-diagnostic levels of these parameters are associated with subsequent pancreatic cancer risk. Methods: A total of 33,346 subjects participated in a health...

... and TRAM. LPS can act not only on immune cells but also on some types of epithelial cells including cancer cells and promote its transformed phenotype. Specifically, LPS can activate NF-ĸB signaling in pancreatic cancer cells, thus connecting inflammation with cancer progression. The TLR4 signaling pathway...