Background: Endoscopic ultrasonography (EUS)-guided choledochoduodenostomy (CDS) is as an alternative to percutaneous transhepatic biliary drainage (PTBD) in patients with biliary obstruction when endoscopic retrograde biliary drainage (ERBD) is unsuccessful. Purpose: We reviewed our experience and technique in patients undergoing EUS-CDS. Patients: Over a 2-year period to December 2008, 15 patients with unsuccessful ERBD underwent EUS-CDS. Methods: EUS-guided needle puncture was performed to access the bile duct from the duodenal bulb. After cholangiography, a guidewire was inserted through the needle and directed to the hepatic hilum. The punctured fistula was then dilated with a biliary dilator and a plastic stent was inserted. Results: The technical success rate of EUS-CDS was 93% (14/15 patients); 1 patient underwent an EUS-guided rendezvous approach because the choledochoduodenal fistula could not be dilated. Decompression of the bile duct was achieved in all patients. Complications included cholangitis in 4 patients, self-limiting local peritonitis in 2 and distal stent migration in 1 patient. The median follow-up time was 125 days and the median duration of stent patency was 99 days. Conclusion: EUS-CDS may be effective for patients following unsuccessful ERBD and offers an attractive alternative to PTBD.

1.
Huibergstse K, Kimmery MB: Endoscopic retrograde cholangiopancreatography, endoscopic sphincterotomy and endoscopic biliary and pancreatic drainage; in Yamada T (ed): Textbook of Gastroenterology. Philadelphia, Lippincott, 1995, pp 2590–2627.
2.
Choudari CP, Sherman S, Fogel EL, et al: Success of ERCP at a referral center after a previously unsuccessful attempt. Gastrointest Endosc 2000;52:478–483.
3.
Ferruccci JT Jr, Mueller PR, Harbin WP: Percutaneous transhepatic biliary drainage: technique, result, and applications. Radiology 1980;135:1–13.
4.
Harbin WP, Mueller PR, Ferrucci JT Jr: Transhepatic cholanginography: complications and use patterns of the fine-needle technique: a multi-institutional survey. Radiology 1980;135:15–22.
5.
Smith AC, Dowsett JF, Russsell RC, et al: Randomized trial of endoscopic stenting versus surgical bypass in malignant low bile duct obstruction. Lancet 1994;344:1655–1660.
6.
Sakamoto H, Kitano M, Nishio T, et al: Value of computed tomography for evaluating the injection site in endosonography-guided celiac plexus neurolysis. Dig Endosc 2006;18:206–211.
7.
Kanazawa M, Yoshihara K, Abel H, et al: Two case reports on intra-tumor injection therapy of dendritic cells (in Japanese). Gan To Kagaku Ryoho 2005;32:1571–1573.
8.
Kitano M, Sakamoto H, Komaki T, et al: Present status and future perspective of EUS-guided drainage. Dig Endosc 2009;21:66–70.
9.
Will U, Fueldner F, Thieme AK, et al: Transgastric pancreatography and EUS-guided drainage of the pancreatic duct. J Hepatobiliary Pancreat Surg 2007;14:377–382.
10.
Giovannini M, Moutardier V, Pesenti C, et al: Endoscopic ultrasound-guided bilioduodenal anastomosis: a new technique for biliary drainage. Endoscopy 2001;33:898–900.
11.
Carr-Locke DL: Overview of the role of ERCP in the management of diseases of the biliary tract and the pancreas. Gastrointest Endosc 2002;56(suppl 6):S157–S160.
12.
Raymondos K, Panning B, Bachem I, et al: Evaluation of endoscopic retrograde cholangiopancreatography under conscious sedation and general anesthesia. Endoscopy 2002;34:721–726.
13.
Wright BE, Case OW, Freeman ML: ERCP in patients with long-limb Roux-en Y gastrojejunostomy and intact papilla. Gastrointest Endosc 2000;52:478–483.
14.
Lameris JS, Stoker J, Nijs HG, et al: Malignant biliary obstruction: percutaneous use of self-expandable stents. Radiology 1991;179:703–707.
15.
Beissert M, Wittenberg G, Sandstede J, et al: Metallic stents and plastic endoprostheses in percutaneous treatment of biliary obstruction. Z Gastroenterol 2002;40:503–510.
16.
Kama NA, Coskun T, Yuksek YN, et al: Factors affecting post-operative mortality in malignant biliary tract obstruction. Hepatogastroenterology 1999;46:103–107.
17.
Burmester E, Niehaus J, Leineweber T, et al: EUS-cholangio-drainage of the bile duct: report of 4 cases. Gastrointest Endosc 2003;57:246–251.
18.
Puspok A, Lomoschitz F, Dejaco C, et al: Endoscopic ultrasound guided therapy of benign and malignant biliary obstruction: a case series. Am J Gastroenterol 2005;100:1743–1747.
19.
Kahaleh M, Wang P, Shami VM, et al: Drainage of gallbladder fossa fluid collections with endoprosthesis placement under endoscopic ultrasound guidance: a preliminary report of two cases. Endoscopy 2005;37:393–396.
20.
Ang TL, Teo EK, Fock KM: EUS-guided transduodenal biliary drainage in unresectable pancreatic cancer with obstructive jaundice. JOP 2007;8:438–443.
21.
Yamao K, Sawaki A, Takahashi K, et al: EUS-guided choledochoduodenostomy for palliative biliary drainage in case of papillary obstruction: report of 2 cases. Gastrointest Endosc 2006;64:663–667.
22.
Yamao K, Bhatia V, Mizuno N, et al: EUS-guided choledochoduodenostomy for palliative biliary drainage in patients with malignant biliary obstruction: results of long-term follow-up. Endoscopy 2008;40:340–342.
23.
Tarantino I, Barresi L, Repici A, et al: EUS-guided biliary drainage: a case series. Endoscopy 2008;40:336–339.
24.
Fujita N, Noda Y, Kobayashi G, et al: Histological changes at an endosonography-guided biliary drainage site: a case report. World J Gastroenterol 2007;13:5512–5515.
25.
Itoi T, Itokawa F, Sofuni A, et al: Endoscopic ultrasound-guided choledochoduodenostomy in patients with failed endoscopic retrograde cholangiopancreatography. World J Gastroenterol 2008;14:6078–6082.
26.
Hanada K, Iiboshi T, Ishii Y: Endoscopic ultrasound-guided choledochoduodenostomy for palliative biliary drainage in cases with inoperable pancreas head carcinoma. Dig Endosc 2009;21(suppl 1):S75–S78.
27.
Park do H, Koo JE, Oh J, et al: EUS-guided biliary drainage with one-step placement of a fully covered metal stent for malignant biliary obstruction: a prospective feasibility study. Am J Gastroenterol 2009;104:2168–2174.
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