..., but the clinical course remains highly variable among individual patients. There is an unmet need for prognostic or predictive biomarkers in this important group of patients. Recently, we have identified circulating glypican-4 (GPC4) as a new biomarker of inferior outcomes in patients with metastatic colorectal...

..., and successfully developed a panel using three of these miRNAs. This panel may serve as a new biomarker tool with high sensitivity and specificity to diagnose UCa in patients. [email protected] [email protected] Urothelial carcinoma (UCa) is among the most common malignancies of the genitourinary system...

... of plasma HSP90α could be a reliable biomarker in diagnosing lung cancer and its subtypes and might be a valid biomarker for predicting lung cancer relapse in patients treated with chemoradiotherapy and surgery. [email protected] 22 04 2021 24 08 2021 21 09 2021 © 2021 S. Karger...

... that LINC01061 is a novel biomarker for diagnosis and prognosis of GC. LINC01061 promoted progression of GC through cell cycle regulation and EMT. [email protected] 23 11 2019 29 04 2020 28 04 2021 © 2021 S. Karger AG, Basel Copyright / Drug Dosage / Disclaimer Copyright...

... response to the immunotherapy. A case can be made here for the use of ICI therapy in undifferentiated/rare tumors with predictable biomarkers and a lack of standard treatment options. Each author meets the criteria for authorship as specified by the ICMJE. Published research complied...

... of breast cancer, high LRG1 levels are associated with lymphatic metastasis, histological grade, poor DFS, and poor OS. This study validates the use of LRG1 as a potential prognosis biomarker for early breast cancer. 28 04 2020 15 08 2020 26 11 2020 © 2020 S. Karger AG, Basel...

... further suggested an association between GM II expression and prognosis of patients with breast cancer. High GM II expression is a potential and independent prognostic biomarker in ccRCC. The inhibition of GM II by transfecting with GM II-shRNA could reduce the proliferation and migration of ccRCC...

... as contributing factors to cancer development, and can be used as novel biomarkers for early diagnosis or even treatment. In this article, we study the newest lncRNAs and their role in thyroid cancer. Homeobox transcript antisense RNA (HOTAIR) is a 2,000 bp lncRNA that encodes antisense to the HOXC locus [ 44...

... status ERCC1 Biomarker Prognosis There are at least 4 pathways of DNA repair that operate on specific types of damaged DNA; these comprise the base excision repair (BER), the nucleotide excision repair (NER), the mismatch repair (MMR), and the double-strand break repair (DDSBR) pathway [ 1...

... changes in clonal composition over time and thus allow dynamic treatment stratification. Today, the routine clinical use of liquid biopsy diagnostic tests is limited; however, in the near future, they might become commonly used sensitive and specific biomarkers to guide cancer treatment. This review...

... Therapie des fortgeschrittenen Stadiums ändert sich dies allmählich. Zunächst galt die Androgenrezeptor-Splice-Variante AR-V7 als vielversprechender Biomarker für die Therapiesteuerung, woran sich zunehmend Zweifel mehren. Inzwischen gibt es jedoch eine Reihe von weiteren neuen, noch nicht zugelassenen und...

... charge around € 500 for analysis of only 1 gene, but this varies considerably on an international level (personal information). Biomarker Costs Gastrointestinal stromal tumor Tyrosine kinase Kit Platelet-derived growth factor receptor alpha Mutational analysis Imatinib Sunitinib Regorafenib...

... the low Ki67-Li group (PFS 14 vs. 10%; p = 0.02). Yet, we found no statistical differences in prognosis for stage I and II patients and in OS for stage IV patients between high versus low Ki67-Li (p > 0.05). Conclusion: Our results suggest that high Ki67-Li can be an independent prognostic biomarker...

... be a biomarker for aggressive forms of ESCC and poor patient prognosis. VEGF-C expression in tumor cells initiates tumor progression and metastasis by stimulation of VEGF receptor (VEGFR)-2 and -3, which are cell surface tyrosine kinase receptors expressed on vascular and lymphatic endothelial cells...

... complete response (pCR) after NAT is a very good predictor for long-term outcome. Clinical factors, such as age and body mass index, as well as recently identified biomarkers can predict the chance of achieving a pCR. Hormone-receptor status, proliferation markers, immune infiltrates and genetic...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2014 Survival Gastric cancer eIF3f Biomarker Prognosis Gastric cancer (GC) is the fourth most common cancer worldwide and the second most common cause of cancer...