Introduction: Soft tissue sarcomas (STSs) are rare diseases. A high level of standardization and centralization was lacking in Germany until 2018. Methods: By developing an evidence-based guideline and a certification system for sarcoma centres, foundations for structured, guideline-based, and centralized sarcoma care were defined. First results of the certified sarcoma centres are presented. Results: The first 3 years of data collection show good results for case volume, presentation rates in pretherapeutic and postoperative tumour boards, psycho-oncological counselling, and study rates. However, other indicators (e.g., preoperative or postoperative radiotherapy for operated high-risk STS without GIST, counselling rates social services) still have potential for improvement. Based on these results, the set of indicators could be further improved. Conclusions: A sarcoma-specific quality assurance scheme that includes guideline-derived quality indicators was developed. In future, a broader database will allow further insights into sarcoma care in Germany.

1.
Robert Koch-Institut
Gesellschaft der epidemiologischen Krebsregister in Deutschland e.V. (Hrsg) Krebs in Deutschland für 2017/2018. 13. Ausgabe
Berlin
Robert Koch-Institut
2021
.
2.
Ressing
M
,
Wardelmann
E
,
Hohenberger
P
,
Jakob
J
,
Kasper
B
,
Emrich
K
.
Strengthening health data on a rare and heterogeneous disease: sarcoma incidence and histological subtypes in Germany
.
BMC Public Health
.
2018
;
18
(
1
):
235
.
3.
Blay
J-Y
,
Honoré
C
,
Stoeckle
E
,
Meeus
P
,
Jafari
M
,
Gouin
F
.
Surgery in reference centers improves survival of sarcoma patients: a nationwide study
.
Ann Oncol
.
2019
;
30
(
8
):
1407
153
.
4.
Gantzer
J
,
Di Marco
A
,
Fabacher
T
,
Weingertner
N
,
Delhorme
JB
,
Brinkert
D
.
Conformity to clinical practice guidelines at initial management in adult soft tissue and visceral tumors since the implementation of the NetSarc network in eastern France
.
Oncologist
.
2019
;
24
(
8
):
e775
783
.
5.
Derbel
O
,
Heudel
PE
,
Cropet
C
,
Meeus
P
,
Vaz
G
,
Biron
P
.
Survival impact of centralization and clinical guidelines for soft tissue sarcoma (A prospective and exhaustive population-based cohort)
.
PLoS One
.
2017
;
12
(
2
):
e0158406
.
6.
Schoffer
O
,
Roessler
M
,
Bierbaum
V
Wirksamkeit der Versorgung in onkologischen zentren (WiZen)
.
2022
. Available from: https://innovationsfonds.g-ba.de/beschluesse/wizen-wirksamkeit-der-versorgung-in-onkologischen-zentren.111 (Accessed Dec 7, 2022).
7.
Jorgensen
PH
,
Lausten
GS
,
Pedersen
AB
.
The Danish sarcoma database
.
Clin Epidemiol
.
2016
;
8
:
685
90
.
8.
German Guideline Programme in Oncology (GGPO)
S3 Guideline for soft-tissue sarcoma in adults
.
2021
. Available from: https://www.leitlinienprogramm-onkologie.de/leitlinien/adulte-weichgewebesarkome/ (Accessed Aug 18, 2022).
9.
German Guideline Program in Oncology (German Cancer Society, German Cancer Aid, Association of the Scientific Medical Societies) (2021) Development of guideline-based quality indicators: methodology for the German Guideline Program in Oncology, version 3. 2021. Available from: http://www.leitlinienprogramm-onkologie.de/methodik/informationen-zur-methodik/ (Accessed Aug 18, 2022).
10.
German Guideline Programme in Oncology (GGPO)
S3 Guideline for soft-tissue sarcoma in adults, Guideline report Version 1.1
.
2022
. Available from: https://www.leitlinienprogramm-onkologie.de/leitlinien/adulte-weichgewebesarkome/ (Accessed Nov 18, 2022).
11.
Hoekstra
HJ
,
Haas
RLM
,
Verhoef
C
,
Suurmeijer
AJH
,
van Rijswijk
CSP
,
Bongers
BGH
.
Adherence to guidelines for adult (Non-GIST) soft tissue sarcoma in the Netherlands: a plea for dedicated sarcoma centers
.
Ann Surg Oncol
.
2017
;
24
(
11
):
3279
88
.
12.
Sarcoma National Managed Clinical Network. North, south east and west of Scotland cancer networks audit report sarcoma quality performance indicators. clinical audit data: 01 April 2014 to 31 March 2015. 2016 (Accessed Sep 9, 2022). Available from: https://www.ssn.scot.nhs.uk/wp-content/uploads/2017/04/Final_Published_National_Sarcoma_QPI_Audit_Report_v1_0_160516.pdf.
13.
Swiss Sarcoma Network (SSN)
Quality Indicators: standards of care based on CPG’s
Luzern
Swiss Sarcoma Network (SSN)
2020
. Available from: https://www.swiss-sarcoma.net/pdf/indicators_of_quality.pdf (Accessed Oct 10, 2022).
14.
Kowalski
C
,
Graeven
U
,
von Kalle
C
,
Lang
H
,
Beckmann
MW
,
Blohmer
JU
.
Shifting cancer care towards Multidisciplinarity: the cancer center certification program of the German cancer society
.
BMC Cancer
.
2017
;
17
(
1
):
850
.
15.
German Cancer Society (DKG)
Catalogue of requirements for certified sarcoma centres 2022
Berlin
German Cancer Society (DKG)
2022
. Available from: https://www.krebsgesellschaft.de/zertdokumente.html (Accessed Aug 18, 2022).
16.
German Cancer Society (DKG)
Data sheet for certified sarcoma centres 2022
Berlin
German Cancer Society (DKG)
2022
. Available from: https://www.krebsgesellschaft.de/zertdokumente.html (Accessed Aug 18, 2022).
17.
German Cancer Society (DKG)
Annual report of the certified sarcoma centres 2022
Berlin
German Cancer Society (DKG)
2022
. Available from: https://www.krebsgesellschaft.de/jahresberichte.html (Accessed Aug 18, 2022).
18.
Blay
JY
,
Le Cesne
A
,
Penel
N
,
Bompas
E
,
Chevreau
C
,
Duffaud
F
.
The nationwide cohort of 26,883 patients with sarcomas treated in NETSARC reference network between 2010 and 2015 in France: major impact of multidisciplinary board presentation prior to 1st treatment
.
Ann Oncol
.
2016
27
Suppl 6
vi483
92
.
19.
Paik
B
,
Seo
CJ
,
Tan
JW
,
Juan
WKD
,
Soo
KC
,
Ong
CAJ
.
A systematic review of margin status in retroperitoneal liposarcomas: does the R0 margin matter
.
Front Oncol
.
2022 Aug 11
12
891710
.
20.
Perera
JR
,
AlFaraidy
M
,
Ibe
I
,
Aoude
A
,
Acem
I
,
van de Sande
MAJ
.
Intermuscular extremity myxoid liposarcoma can be managed by marginal resection following neoadjuvant radiotherapy
.
Eur J Surg Oncol
.
2022 Sep 27
49
2
362
7
.
21.
Eichler
M
,
Singer
S
,
Hentschel
L
.
Die psychoonkologische Versorgungssituation von Patienten mit Weichteilsarkomen
.
Onkologie
.
2022
22.
Savina
M
,
Le Cesne
A
,
Blay
JY
,
Ray-Coquard
I
,
Mir
O
,
Toulmonde
M
.
Patterns of care and outcomes of patients with METAstatic soft tissue SARComa in a real-life setting: the METASARC observational study
.
BMC Med
.
2017
;
15
(
1
):
78
.
23.
Bonvalot
S
,
Gronchi
A
,
Le Péchoux
C
,
Swallow
CJ
,
Strauss
D
,
Meeus
P
.
Preoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC-62092: strass): a multicentre, open-label, randomised, phase 3 trial
.
Lancet Oncol
.
2020 Oct
21
10
1366
77
.
24.
Fayet
Y
,
Tétreau
R
,
Honoré
C
,
Le Nail
LR
,
Dalban
C
,
Gouin
F
.
Determinants of the access to remote specialised services provided by national sarcoma reference centres
.
BMC Cancer
.
2021
;
21
(
1
):
631
.
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