Beim metastasierten kastrationsresistenten Prostatakarzinom (mCRPC) erfolgt heute eine Sequenztherapie. Daher müssen sich neue Wirkstoffe, die früher - im nicht-metastasierten kastrationsresistenten Stadium (M0CRPC) mit hohem Metastasierungsrisiko - eingesetzt werden, ebenfalls in diese Sequenz einfügen.

Keywords:
Prostatakarzinom, ­Sequenztherapie, Resistenzen
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Smith MR et al.: AACR 2018;abstr 2605, www.abstractsonline.com/pp8/#!/4562/presentation/2711 (letzter Zugriff: 14.02.2019).
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Smith MR et al.: N Engl J Med 2018;378:1408-1418 & Appendix.
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Fachinformation Erleada®, Stand Januar 2019.
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