Hinsichtlich unserer Erwartungen in die pharmakologische Wirksamkeit konventionell verordneter Medikamente (HÄmorheologika, HÄmodilutiva, Vasodilativa, Histaminderivate, Kalziumantagonisten, Prostazyklinanaloga, Nootropika wie z.B. Ginkgo bilobÄ) bei Patienten mit einer akuten idiopathischen InnenohrschwerhÖrigkeit (einem sogenannten HÖrsturz), oder Knall- oder LÄrmtraumata sind die in der vorliegenden Übersicht referierten klinischen Studienergebnisse ernÜchternd. Prednisolon scheint hingegen bei einem moderaten idiopathischen HÖrverlust im Tief- und Hochtonbereich hinsichtlich der HÖrverbesserung signifikant besser wirksam zu sein als eine Plazebotherapie. Im zweiten Teil werden aktuelle experimentelle Forschungsergebnisse Über die Thematik referiert, die dem Kliniker hoffnungsvoUe neue therapeutische AnsÄtze anbieten kÖnnen.

Keywords:
Innenohrschwerhörigkeit, Tinnitus, Therapie, Hämorheologie, Hämodilution, Kortison, Hyperbare Oxygenation, Experimentelle Studien,, Meerschweinchen Klinische Studien, Menschen
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© 1995 S. Karger AG, Basel
1995
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