Die Behandlung langstreckiger Trachealstenosen gehÖrt immer noch zu den besonders schwierigen Aufgaben der Hals-Nasen-Ohrenheilkunde. Neben den Erweiterungsplastiken der Trachea, der Therapie mit Platzhaltern und der Segmentresektion kommt die Versorgung mit einer Prothese in Betracht. Die Anforderungen an Trachealprothesen im Hinblick auf BiokompatibilitÄt und physikalische Eigenschaften sind hoch. Ein von uns vorgeschlagenes Implantat wurde bezÜglich der Morphologie und der mechanischen Belastbarkeit der menschlichen Trachea nachgebildet. Im Tierversuch konnte diese Prothese als zirkumferenter LuftrÖhrenersatz verwendet werden. Erste Implantationen bei Patienten fÜhrten in zwei von drei Fallen zu einem zufriedenstellenden Abschluss der Stenosebehandlung.

Keywords:
Trachealstenose, Trachealersatz, Künstliche Organe, In-vitro-Tests, Tierexperimente, Klinische Resultate
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© 1992 S. Karger AG, Basel
1992
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