Background: Surgical therapy for T2 glottic carcinoma still is a topic of controversial discussion. The value of laser therapy in this stage of disease is difficult to determine due to selection bias. Data of comparative analyses have usually been collected from retrospective studies which are more prone to selection bias. Patients and Methods: A total number of 14 patients suffering from T2 glottic carcinoma were treated by transoral laser microsurgery. Results: During the median follow-up of 24 months, 2 patients developed recurrent disease in the anterior commissure, and 12 patients remained free of disease. Conclusion: Endoscopic laser therapy should be considered after weighing up the indication thoroughly. The sometimes extremely difficult conditions in transoral laser surgery are tightly bound to the experience of the operating surgeon and in cases of doubt, conventional partial laryngectomy should be preferred.

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