... cholesteatoma, jugular foramen schwannoma, and giant-cell tumor. The follow-up duration ranged from 2 to 24 months. No tumor recurrence or growth was encountered in the follow-up. The operations were uneventful. Total surgical excision could be achieved in 10 patients. A second-stage retrosigmoid approach...

...Sunil Dutt Sharma; Ahmad Hariri; Ravi Kumar Lingam; Arvind Singh Background: Non-echoplanar diffusion-weighted MRI (DWMRI) has a role in the surgical planning for cholesteatoma. Aims/Objectives: The aim of the study was to assess the use of DWMRI in the management of cholesteatoma across the UK...

... (COM), the surgeon may encounter several problems. The aim of this study was to evaluate the impact of COM with and without cholesteatoma on surgical and auditory outcomes of CIs. Methods: The study group consisted of 39 patients with COM who received CIs. Age- and gender-matched 38 standard CI...

.... Methods: A total of 258 patients who underwent mastoidectomy and tympanoplasty for chronic otitis media with cholesteatoma from 2010 to 2014 were reviewed. The radiological diagnoses were compared with intraoperative findings. Sensitivity and specificity of 2.0-, 1.5-, 1.0-, and 0.75-mm-thick computed...

.... Endoplasmic reticulum stress Unfolded protein response Chronic otitis media Cholesteatoma Otitis media is a common term for inflammatory changes that occur in the middle ear. It is one of the most common diseases in otorhinolaryngology and can be classified according to how rapid the onset...

...Badr Eldin Mostafa; Lobna El Fiky Background: Congenital cholesteatomas (CC) arise from epithelial remnants around the petrous bone. They enlarge gradually causing progressive destruction and functional damage to the ear and surrounding structures. Because of their insidious course, most patients...

... Cholesteatoma Over the last decade, indications for Vibrant Soundbridge TM (VSB) implantation have widened from pure sensorineural hearing loss to combined hearing losses by introducing different modalities for coupling of the floating mass transducer (FMT). In cases of a stapes superstructure, the FMT...

...Amir Minovi; Tobias Dombrowski; Shabnam Shahpasand; Stefan Dazert In this retrospective study, we evaluated the audiometric results after using the retrograde mastoidectomy technique with open mastoid cavity for the removal of extended attic cholesteatomas. The described technique was used...

...Michele Cavaliere; Antonella Miriam Di Lullo; Antonia Caruso; Giandomenico Caliendo; Andrea Elefante; Arturo Brunetti; Maurizio Iengo We have analyzed the preoperative diagnosis of cholesteatoma through the use of diffusion-weighted intensity magnetic resonance (DWI-MR) in 16 consecutive patients...

... ear cholesteatoma compared to the skin of the normal external auditory canal (EAC). The expression of TWEAK was analyzed using reverse transcription-polymerase chain reaction, Western blotting and immunohistochemical staining. TWEAK expression was correlated with that of TNF-α as determined by Western...

... were determined by Western blot analysis of tissue samples obtained during ear surgery. The expression levels of TNF-α, IL-1α and IL-6 in cholesteatoma tissues were substantially higher compared to those determined in the granulation tissue. The highest levels of TNF-α, IL-1 and IL-6 proteins were...

...Takuo Haruyama; Masayuki Furukawa; Takeshi Kusunoki; Junko Onoda; Katsuhisa Ikeda Purpose: The present study was designed to elucidate the immunoreactivity and protein level of IL-17 in human cholesteatomas. Procedures: The expression and localization of IL-17 and receptor activator of nuclear...

...Zhi Gang Zhang; Sui Jun Chen; Wei Sun; Yi Qing Zheng Objectives: To present an effective system for the evaluation and surgical management of localized attic cholesteatoma, as well as describing the follow-up of patients treated at our institution. Study Design: Retrospective review of single...

...P. Montandon; M. Benchaou; J.P. Guyot Mastoid tympanoplasty with a canal wall-up technique provides better conditions for a healthy skin lining than canal wall-down techniques. The formation of retraction pockets in residual pneumatized cavities is however a major cause of cholesteatoma recurrence...

...Alaa El Seifi; Bassem Fouad Although using autogenous ossicles in reconstruction offers stable hearing results with good tendency for healing and minimal extrusion, their use in cholesteatomatous ears has been criticized for the possibility of progressive osteitis, bone resorption and cholesteatoma...

...Carsten Wennmo; Hannes Petersen; Knut Flisberg This is a retrospective study of a limited group of 30 patients, children and adults, diagnosed as having cholesteatomas. Analysis includes audiological data and surgical results. Two techniques were used in surgery. In half of the cases...

...Jesús Bujía; Anja Holly; Holger Sudhoff; Francisco Antolí-Candela; Mario Guzman Tapia; Ernst Kastenbauer Cholesteatoma epithelium is characterized by a keratinocyte dysregulation with aggressive growth subsequently destroying the middle ear mucosa. The monoclonal antibody Ki-67 recognizes a nuclear...

... and in 25 % the other semicircular canals and/or the cochlea were involved. The fistula test was positive in 50 % of the cases. The surgical technique used in all 20 cases was a one-stage closed tympanoplasty, i.e. removal of the cholesteatoma matrix, covering of the fistula with fascia and bone...

... through the labyrinth. During the acute stage of intracranial abscess formation, the site of intracranial invasion showed a destructive inflammatory reaction characterized by the presence of granulations, resorption and sequestration of bone, invasive cholesteatoma, collections of purulent exudate...

...- and extracranial otogenic complications (posterior fossa syndrome, labyrinthine fistula, labyrinthitis, facial palsy) mostly due to cholesteatoma, and a less frequent intracranial complication occurring mainly in children (otitic hydrocephalus) caused by chronic otitis media. It may therefore be concluded...