The serum levels of circulating immune complexes were studied in 63 patients and the complement system in 36 patients with Bell’s palsy. The IgG-Clq and IgG-C3 containing immune complexes were analyzed by an enzyme-linked immunosorbent assay. The levels were found to be significantly elevated in the acute and convalescent stages of the palsy compared with controls. The total complement activity as determined by a CH50 assay and complement component C3 titrations also showed elevated values. The levels of C2 were not altered. The results indicate in Bell’s palsy an inflammatory process and an antigen-antibody response which may be triggered by a viral antigen.

Keywords:
Bell’s palsy, Circulating immune complexes, Enzyme-linked immunosorbent assay, Complement component C2, C3, CH50 assay, Inflammation, Virus, Antigen
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© 1987 S. Karger AG, Basel
1987
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