Abstract
After unilateral labyrinthectomy in the frog, the difference between the compound activities of the neck muscles on both sides is taken as a parameter of the state of the equilibrium system. By this means the strong disturbing effect of monoaminergic and histaminergic substances and the beneficial effect of their blockers on the so-called compensation have been tested. From the results a peripheral site of action becomes probable. This is in agreement with behavioural studies and demonstrates a pharmacological influence on the plasticity of the nervous system including its peripheral feedback loops.
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© 1982 S. Karger AG, Basel
1982
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