...Wenna Gao; Xuemin Jin; Pengyi Zhou; Haiyan Zhu; Kunpeng Xie; Bo Jin; Liping Du Uveitis, a complicated group of ocular inflammatory diseases, can be affected by massive pathogenic contributors such as infection, autoimmunity, and genetics. Although it is well known that many pathological changes...

...Jun Zhang; Peng Zhou; Shuqiong Hu; Jian Qi Background: Though the risk of protein tyrosine phosphatase nonreceptor 22 ( PTPN22 ) and cytotoxic T-lymphocyte antigen-4 ( CTLA-4 ) genetic variants with uveitis have been developed, the combined results still remain uncertain and controversial...

...Weiting Liao; Zhenyu Zhong; Guannan Su; Xiaojie Feng; Liping Du; Fu-Zhen Li; Lingyu Dai; Aize Kijlstra; Peizeng Yang Introduction: Immunosuppressive therapy for uveitis may cause liver damage. Methods: To investigate incidence of liver damage during uveitis treatment, we compared serological...

...Kemal Tekin; Yasemin Ozdamar Erol; Merve Inanc; Mustafa Fevzi Sargon; Pinar Cakar Ozdal; Nilufer Berker Purpose: To investigate the transmission electron microscopic findings of lens epithelial cells (LECs) in patients with different subtypes of uveitis and to compare the findings with those in age...

...Yue Guo; Ruiping Gu; Jian Yu; Boya Lei; Dekang Gan; Gezhi Xu Purpose: To demonstrate the anti-inflammatory action of a synthetic glucocorticoid-induced leucine zipper (GILZ 98–134 ) peptide (GILZ-p) in a model of endotoxin-induced uveitis (EIU) in rats. Methods: The EIU model was induced in Sprague...

...Aseef Ahmed; C. Stephen Foster Purpose: Vision-threatening ocular inflammation can be a devastating complication of granulomatosis with polyangiitis (GPA). Here we performed a retrospective observational study to describe the safety and efficacy of treating scleritis and uveitis with either...

...Cem Ozgonul; Cagri Giray Besirli Ocular toxoplasmosis, a chorioretinal infection with Toxoplasma gondii , is the most common etiology of posterior uveitis in many countries. Accurate diagnosis depends heavily on the characteristic clinical features of this disease, but atypical presentations...

...Jane M. Wells; Justine R. Smith Uveitis is a common association of juvenile idiopathic arthritis (JIA) that has previously been characterized by poor visual prognosis with limited options for effective treatment. Since corticosteroid treatment is not a preferred long-term option for most patients...

.... Immunology Ocular toxoplasmosis Pathology Toxoplasma gondii Uveitis The obligate intracellular protozoan parasite Toxoplasma gondii is an important opportunistic agent that infects all warm-blooded vertebrates including humans. Two major routes of infection exist. First, humans may become...

...Ahmed M. Karara; Tamer A. Macky; Mai H. Sharawy Purpose: To investigate the prevalence and pattern of uveitis in patients with multiple sclerosis (MS). Patients and Methods: This is a cross-sectional, observational, descriptive clinical study of patients with MS who had complete ophthalmological...

...Carsten Heinz; Suphi Taneri; Martin Roesel; Arnd Heiligenhaus Background: To compare the influence of central corneal thickness (CCT) during active anterior uveitis and after resolution on intraocular pressure (IOP) measurements by Goldmann applanation tonometry (GAT) and by dynamic contour...

... was established most commonly by bilateral hilar lymphadenopathy (96.2%), histopathology (46.9%) or other organ manifestations. The initial clinical presentation of sarcoidosis (mean age 34.1 ± 10.8 years) had often been eye manifestation (21.2%). Within this group, anterior uveitis was most common (76.4...

...Tae Wan Kim; Hum Chung; Hyeong Gon Yu Background: To compare the expression of chemokines in the aqueous humor and chemokine receptors in intraocular lymphocytes from Behçet and non-Behçet uveitis patients. Methods: A total of 95 uveitis patients were included in this study. We studied 39 Behçet...

...Nava Naveh; Andrei Nussbaum; Howard Desatnik; Elisha Bartov The effect of rabbit vitreous with endotoxin-induced uveitis was investigated for its role in the modulation of rat corneal neovascularization (NV). Elvax pellets implanted into at cornea contained either uveitic vitreous, intact vitreous...

... is also suspected in the pathogenesis of some types of uveitis believed to involve autoimmune mechanisms, such as Behçet’s disease. We report our results on the role of HSP60 in patients with uveitis. HSP60 was subjected to electrophoresis in immunoblot analysis, and then allowed to react with sera from...

...İclal Yücel; Nadir Paksoy; Gültekin Yücel; Güler Aksu; Aslan Aksu In order to assess the role of vitamin E, an antioxidant, in the treatment of uveitis, a controlled experimental study was carried out on 20 New Zealand albino rabbits with bovine-albumin-induced uveitis. In all vitamin-E-treated...

... of superoxide by stimulated neutrophils. In experimental allergic uveitis induced by sensitization with retinal’s’ antigen, treatment with adenosine produced a marked reduction in the expected inflammation. 4 03 1987 24 09 1987 10 12 2009 © 1988 S. Karger AG, Basel 1988 Copyright / Drug...

...Yvonne de Kozak; Jean-Phillip Nordman; Jean-Piere Faure; Narsing A. Rao; George E. Marak, Jr. The antioxidant enzymes superoxide dismutase and glutathione peroxidase have been observed to be effective antiphlogistic agents in severe experimental allergic uveitis induced by retinal S antigen in rats...

...Kiwamu Sasaki; Hiroki Sanui; Hajime Inomata In order to investigate possible immunopathogenic mechanisms in the recurrence of uveitis, cross-reactive proteins were tested for their capacity to induce experimental uveitis. Guinea pigs were immunized with porcine serum albumin (PSA) in complete...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Uveitis Lymphocytes Inflammatory aqueous humor Immunoregulation in uveitis Ophthalmic Res 1991;23:59-65 © 1991 S...