... (SC) area, trabecular meshwork (TM) thickness and length, scleral spur (SS) length, and anterior scleral thickness (AST) were measured using swept-source optical coherence tomography. Associations between SC area, TM thickness, TM length, SS length, and AST were also estimated. Results: SC area, TM...

... in the occurrence and development of glaucoma and widely participate in regulating biological processes of glaucoma-related genes. This article reviews the connection between the aqueous humor, trabecular meshwork, the apoptosis of retinal ganglion cells, and miRNA. [email protected] wangjiantao65@126...

..., and free radicals to induce irreversible deleterious effects on different eye tissues. These processes may lead to cataract formation in the lens, loss of corneal endothelial cells, modification of the glycosaminoglycan secretory patterns of the cells of the trabecular meshwork, and other changes...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Trabecular meshwork Proteoglycans Glycoproteins Lectins Original Paper Ophthalmic Res...

... in the trabecular meshwork and corneal endothelium. 9 11 1993 13 01 1994 11 12 2009 © 1994 S. Karger AG, Basel 1994 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form...

... by using human trabecular meshwork as the immunogen. One MAB (KAa25D7) consistently recognized two polypeptides with molecular weights of approximately 42 and 49 kilodaltons. The former comigrated with actin and the latter was shown by fractionation and extraction studies to be a macromolecular complex...

...M. Fossarello; S. Carta; Del Fiacco; G. Diaz; N. Orzalesi The ultrastructure of the trabecular meshwork of the anterior chamber angle after corticosteroid-induced ocular hypertension was studied with TEM. A morphometric analysis by means of stereological techniques did not reveal changes...

..., University of Berlin, Berlin Abstract. With the aid of the scanning electron micro­ Key Words scope using4eyes of Rhesus mon keys, 8post mortem eyes Trabecular meshwork and 1 freshly enucleated tumourous eye, the inner and Sinus venosus sclerae outer wall of Schlemm s canal were examined. At the Outer wall...

...Manabu Shinzato; Yoshito Yamashiro; Nariko Miyara; Akihiro Iwamatsu; Kouji Takeuchi; Masato Umikawa; Maitsetseg Bayarjargal; Ken-ichi Kariya; Shoichi Sawaguchi Purpose: To investigate global protein expression profiles in the trabecular meshwork (TM) of normal and glucocorticoid-induced ocular...

...Hagen Thieme; Kirsten Steinhausen; Anna Ottlecz; George N. Lambrou; Olaf Strauss; Michael Wiederholt; Rita Rosenthal Background: The trabecular meshwork (TM) is a smooth muscle-like tissue with contractile properties and by this mechanisms involved in the regulation of aqueous humor outflow...

...Lars Choritz; Rita Rosenthal; Michael Fromm; Michael H. Foerster; Hagen Thieme To clarify the potential role of endothelin-1 (ET-1) in the pathogenesis of glaucoma, the endothelin receptors expressed in bovine trabecular meshwork (TM) and ciliary muscle (CM) were identified. TM and CM strips were...

...Carlo Cavallotti; Janos Feher; Nicola Pescosolido; Paolo Sagnelli Glycosaminoglycans play a central role in maintaining the normal outflow resistance in the human trabecular meshwork. We evaluated the possible morphological, histochemical and morphometrical age-related changes in glycosaminoglycans...

...Willem Kamphuis; Andrea Schneemann Mutations in the gene optineurin (OPTN) have been associated with primary-open angle glaucoma. Here we present a study on the level of OPTN gene expression in the human trabecular meshwork in response to increased perfusion pressure in the anterior chamber...

...Andrea Schneemann; Philip F.J. Hoyng; Willem Kamphuis The purpose of this study was to assess the effects of increased intraocular pressure on the expression levels of the prostanoid receptor genes (DP, EP 1–4 , FP, IP, TP) in the trabecular meshwork of human donor eyes. Anterior segments of human...

... glaucoma (POAG). Basement membranes play key roles in the attachment of the overlying trabecular cells and Schlemm’s canal cells. Methods: Electron microscopy used in conjunction with immunogold labeling was used to examine the ultrastructure of the basement membranes in the trabecular meshwork...

... with a diameter of 2 µm were seen in the vitreous cavity and trabecular meshwork, while nanospheres with a diameter of smaller than 200 nm were also observed in the retina as well as these tissues. Our findings indicated that nanospheres may be beneficial as a drug carrier to the retina, vitreous and trabecular...

... µl/min/mm Hg in human eyes after ab externo trabeculectomy. On histological examinations the aqueous outflow pathway was seen to be at the level of the residual trabecular meshwork. Conclusion: This study showed that ab externo trabeculectomy significantly lowers IOP and improves outflow facility...

... and glaucomatous trabecular meshwork. Methods: Fresh-frozen trabeculectomy specimens from glaucoma patients and trabecular meshwork from human donor eyes were included for immunohistochemistry. We used antibodies against laminin 1 (EHS-laminin/α1β1γ1), laminin 2 (merosin/α2β1γ1), the subunits α2 (M laminin), β1...

...Mariko Sasamoto; Hai-Bo Chen; Shigeo Tsukahara We aimed to provide a detailed analysis of substance P (SP)-containing nerves in the trabecular meshwork by ultrastructural immunohistochemistry and capsaicin treatment for chemical ablation of the sensory nerves. Numerous myelinated and unmyelinated...