..., observational study, 200 eyes treated with IVB for type 1 retinopathy of prematurity (ROP) and aggressive-ROP were included. The pretreatment retinal vascularization was evaluated by analyzing quantitative measurements of optic disc-to-fovea distance (DFD), disc diameter, and shortest and longest distance...

...Jing Feng; Ge Liang; Weiping Gao; Xiaoqin Li; Lin Wei; Hongyu Chang; Xiaorui Zhang; Yong Tao Introduction: The aim of this study was to investigate the relevance of plasma levels of apelin and other risk factors in infants with retinopathy of prematurity (ROP). Methods: This was a single-center...

...Yasmin Islam; Lorick Andersen; Swati Agarwal-Sinha Purpose: Retinopathy of prematurity (ROP) is considered a disease of the inner retina; however, there is increasing evidence that demonstrates choroidal vasculature loss in ROP, leading to degeneration of outer retinal function and visual...

...Sarina M. Amin; Andres Gonzalez; Jade Guevara; Charlotte Bolch; Lorick Andersen; W. Clay Smith; Swati Agarwal-Sinha Introduction: Bevacizumab and ranibizumab, which are anti-vascular endothelial growth factor (VEGF) medications, are used frequently in the treatment for retinopathy of prematurity...

... regressed retinopathy of prematurity (tROP or srROP) to assess the impact on best-corrected visual acuity (BCVA). Methods: CT was measured by SS-OCT (DRI-OCT Triton; Topcon, USA) single scans of a 6-mm diameter around the fovea in 17 children with tROP or srROP (4–7 years of age) and compared to 25 controls...

...Charlotte Pallot; Agnès Soudry Faure; Camille Charvy; Ninon Ternoy; Claire Langlet Muteau; Niyazi Acar; Alain M. Bron; Claude Speeg Schatz; Catherine Creuzot-Garcher Purpose: To determine the factors influencing the time from preterm birth and retinopathy of prematurity (ROP) detection to optimize...

... (MCA) in infants with retinopathy of prematurity (ROP). Materials and Methods: This prospective and interventional study included 15 infants with ROP who were treated with IVB. Peak systolic velocity (PSV), end-diastolic velocity, mean velocity (MV) and resistivity index were measured using pulse wave...

...Abdelrahman G. Salman; Aza M. Said Purpose: To study the structural, visual and refractive outcomes of intravitreal injection of aflibercept monotherapy in patients with high-risk prethreshold type 1 retinopathy of prematurity (ROP). Design: Prospective nonrandomized interventional case series...

...Nan Xiang; Min-Jian Zhao; Xin-Yu Li; Hai-Hong Zheng; Gui-Gang Li; Bin Li Background: Current treatments for retinopathy of prematurity (ROP) targeting single vascular growth factors are ineffective in preventing neoangiogenesis. Methods: We investigated the redundant/compensatory mechanisms between...

...Hong-Ming Cheng; Jing Xiong; Shinjiro Hirose; Hiromasa Igarashi; Tatsuo Hirose We investigated sugar metabolism in lenses isolated from infants with stage-5 retinopathy of prematurity (ROP). The lenses were incubated in 13 C-labeled glucose (35.5 m M ) or galactose (30 m M ) for 24 h at 37.5°C. Six...

.... To elucidate the potential role of Angs and the Tie2 system in retinopathy of prematurity (ROP), we have investigated the expression of Angs, Tie2 and VEGF within fibroproliferative membranes in ROP. Methods: Fibroproliferative membranes were obtained from 38 cases with stage 5 ROP at the time of vitrectomy...