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1-20 of 127
Keywords: Rabbit
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Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (2024) 67 (1): 23–28.
Published Online: 10 December 2023
... in rabbits. Methods: IOP was measured by a pneumatonometer before and after intracameral injection of Hsp90 inhibitors. The aqueous flow rate was measured by fluorophotometry. Trans-epithelial electrical resistance was measured in primary human trabecular meshwork cells. Results: 17-AAG, a specific Hsp90...
Journal Articles
Subject Area:
Ophthalmology
Tatsuhiko Tsujisawa, Hitoshi Ishikawa, Shigekazu Uga, Ken Asakawa, Yusuke Kono, Kimiyo Mashimo, Nobuyuki Shoji
Journal:
Ophthalmic Research
Ophthalmic Res (2022) 65 (5): 595–602.
Published Online: 31 July 2020
... underlying its ability to reduce IOP remain unclear. We therefore investigated the morphological changes and mechanisms of IOP reduction after MP-TSCPC. Methods: The right eyes of 4 pigmented rabbits were treated with MP-TSCPC with power setting corresponding to those used in glaucoma patients (1 power...
Journal Articles
Tissue Plasminogen Activator as an Antiangiogenic Agent in Experimental Corneal Neovascularization in Rabbits
Available to PurchaseSubject Area:
Ophthalmology
Kon-ichi Arai, Tsutomu Yasukawa, Aki Kato, Ayae Kubota, Hideaki Usui, Noriaki Takase, Soichiro Kuwayama, Yuichiro Ogura
Journal:
Ophthalmic Research
Ophthalmic Res (2018) 59 (3): 170–175.
Published Online: 13 March 2018
... vein endothelial cells (HUVECs) was assessed by an XTT assay [2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)- 2 H-tetrazolium-5-carboxanilide]. A basic fibroblast growth factor-impregnated gelatin hydrogel sheet was implanted into the rabbit cornea to induce corneal neovascularization. Immediately...
Journal Articles
Ciliary Tissue Transplantation in the Rabbit Eye: Does the Localization of the Graft Affect Survival?
Available to PurchaseSubject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (2016) 57 (1): 70–76.
Published Online: 08 July 2016
...Hülya Yazıcı; Gökhan Gürelik; Fulya Yaylacıoğlu Tuncay; Pınar Uyar Göçün Purpose: To examine whether ciliary body transplantation is applicable, the graft is viable and the localization of the graft material affects graft survival. Methods: Fifteen female New Zealand white rabbits were used. Three...
Journal Articles
Retinal and Ocular Toxicity in Ocular Application of Drugs and Chemicals – Part I: Animal Models and Toxicity Assays
Available to PurchaseSubject Area:
Ophthalmology
Fernando Marcondes Penha, Eduardo B. Rodrigues, Maurício Maia, Eduardo Dib, Elaine Fiod Costa, Bruno A. Furlani, Milton Nunes Moraes Filho, Juliana L. Dreyfuss, Juliana Bottós, Michel E. Farah
Journal:
Ophthalmic Research
Ophthalmic Res (2010) 44 (2): 82–104.
Published Online: 13 May 2010
... difficult. Mice and rats provide genetically controlled models for investigations. Pigs, dogs and cats represent good large-size animal models, while rabbits are one of the most used species for retinal toxicity evaluations. Various laboratory methods were identified, including light microscopy, electron...
Journal Articles
Evidence against Cannabinoid Receptor Involvement in Intraocular Pressure Effects of Cannabinoids in Rabbits
Available to PurchaseSubject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1997) 29 (1): 1–5.
Published Online: 11 December 2009
...-kylindoles and the arachidonylethanolamides (the endogenous ligands). We examined the IOP effect in normotensive rabbits after systemic administration of an aminoalkylindole, WIN-55,212-2, and of (R)-(+)-methanandamide, a hydrolysis-resistant endogenous ligand derivative. The decrease in IOP for 6 animals...
Journal Articles
Mechanisms of Graft Rejection in the Transplantation of Retinal Pigment Epithelial Cells
Available to PurchaseSubject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1997) 29 (5): 298–304.
Published Online: 11 December 2009
...Leon Kohen; Volker Enzmann; Frank Faude; Peter Wiedemann Purpose: The role of activated retinal pigment epithelium (RPE) cells was investigated in the rejection after subretinal transplantation. Methods: RPE cells from 7 pigmented rabbits were separated and evaluated regarding their MHC class II...
Journal Articles
Innervation of the Ciliary Process Vasculature and Epithelium by Nerve Fibers Containing Catecholamines and Neuropeptide Y
Available to PurchaseSubject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1993) 25 (2): 108–118.
Published Online: 11 December 2009
...M.G. Rittig; K. Licht; R.H.W. Funk The ciliary processes (CPs) in the rat were investigated for the presence of neuropeptide Y (NPY)-like immunoreactivity and for histofluorescence indicating catecholamine (CAM)-ergic innervation in the rat, rabbit and cynomolgus monkey. Special attention was paid...
Journal Articles
The Vessel Architecture of the Pars plana in the Cynomolgus Monkey, Rat and Rabbit Eye: A Scanning Electron Microscopic Study of Plastic Corrosion Casts
Available to PurchaseSubject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1993) 25 (6): 337–348.
Published Online: 11 December 2009
...R.H.W. Funk In the cynomolgus monkey, rabbit and rat the architecture of the pars plana vasculature was investigated using scanning electron micrographs of resin casts. The most complex vessel architecture was found in the cynomolgus monkey. Here, the pars plana venules have affluxes from...
Journal Articles
Effect of Suleparoide on Fibrinolysis in the Anterior Chamber of Rabbits
Available to PurchaseSubject Area:
Ophthalmology
Antonio Lepri, Umberto Benelli, Patrizia Chetoni, Genoveffa Perini, Marco Fabrizio Saettone, Marco Nardi
Journal:
Ophthalmic Research
Ophthalmic Res (1996) 28 (3): 176–183.
Published Online: 11 December 2009
.... A quantitative model of fibrin deposition in the rabbit anterior chamber was used to assess the efficacy of Suleparoide I.N.N. (HHS-5) in preventing fibrin formation and in promoting the clearance of fibrinous membranes. Citrated human plasma was injected intracamerally after paracentesis to induce the formation...
Journal Articles
Intraocular Kinetics of Ceftazidime (Modacin ® )
Available to PurchaseSubject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1992) 24 (3): 150–154.
Published Online: 10 December 2009
...K. Mochizuki; Y. Yamashita; M. Torisaki; M. Komatsu; T. Tanahashi; K. Kawasaki The concentration of ceftazidime was determined in the aqueous humor and the vitreous body of normal, vitrectomized and aphakic/vitrectomized eyes and in the serum of albino rabbits 1 h after intravenous injection...
Journal Articles
Characterization of Esterases Involved in the Hydrolysis of Dipivefrin Hydrochloride
Available to PurchaseSubject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1993) 25 (1): 46–51.
Published Online: 10 December 2009
...Masatsugu Nakamura; Eiichi Shirasawa; Mitsushi Hikida We characterized the interaction of the prodrug dipivefrin hydrochloride (DPE) with esterase activity in the rabbit cornea. The esterases which were identified included: (1) cholinesterase, (2) acetylcholinesterase, (3) a mixture containing car...
Journal Articles
Sustained Decreases in Systemic Blood Pressure Do Not Cause Ocular Hypotension
Available to PurchaseSubject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1989) 21 (1): 37–43.
Published Online: 10 December 2009
... pressure, the effects of two systemic antihypertensive drugs were determined in the conscious rabbit. Topical, unilateral administration of either hydralazine or prizidilol did not lower the intraocular pressure of either eye. A bolus intravenous injection of either hydralazine or prizidilol caused...
Journal Articles
Microendoscopy of the Anterior Segment Vasculature in the Rabbit Eye: (With 1 color plate)
Available to PurchaseSubject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1989) 21 (1): 8–17.
Published Online: 10 December 2009
..., and an estimation of blood oxygenation are possible. Experimental studies with fluorescent dyes can also be performed using special filters. In albino rabbits, no apparent vascular disturbances were observed under certain experimental conditions. Touching a ciliary process with the tip of the endoscope immediately...
Journal Articles
Characterization of the Mechanism of Acute Ocular Irritation to YAG Laser Capsulotomy in Rabbits: Effects of Substance P Antagonists, Met-Enkephalin, Tetracaine and Tetrodotoxin
Available to PurchaseSubject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1989) 21 (5): 360–368.
Published Online: 10 December 2009
...Olli Oksala; Johan Stjernschantz; Kai von Dickhoff This study was undertaken to characterize the mechanism of ocular irritation to YAG laser capsulotomy in rabbits. The blocking agents were administered intravitreally. ( D -Arg 1 , D -Pro 2 , D -Trp 7,9 )-SP, a substance P antagonist, tended...
Journal Articles
Lysosomal Enzyme Activities in Ocular Tissues and Adnexa of Rabbits
Available to PurchaseSubject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1989) 21 (3): 187–190.
Published Online: 10 December 2009
...Keiko Yamaguchi; Seiji Hayasaka; Satoshi Hara; Takashi Shiono; Katsuyoshi Mizuno We examined biochemically the distribution of lysosomal enzyme activities in the ocular tissues and adnexa of albino rabbits using p -nitrophenyl derivatives. The pink and white lobes of Harderian gland disclosed...
Journal Articles
Cholinergic Receptors in the Extraocular Rectus Muscle of the Rabbit
Available to PurchaseSubject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1989) 21 (3): 162–166.
Published Online: 10 December 2009
...A.A.L.M. Rondas; H.W.G.M. Boddeke; H.N. Doods; L. Thörig; N.J. van Haeringen; P.A. van Zwieten The cholinergic receptors in rabbit isolated rectus muscle preparations were characterized by means of cholinergic agonists and antagonists. The concentration-dependent contraction induced...
Journal Articles
Functional Morphology of Rabbit Iridial Ciliary Processes
Available to PurchaseSubject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1989) 21 (3): 249–260.
Published Online: 10 December 2009
... processes. Electron microscopically, the basolateral labyrinth of the PE appeared enormously enlarged, forming wide protein-containing intercellular spaces. These findings suggest that the function of the iridial ciliary processes in rabbits has a dual nature. Under normal circumstances, the main function...
Journal Articles
Timed Biomicroscopy of Rabbit Corneal Wound Repair
Available to PurchaseSubject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1990) 22 (6): 377–382.
Published Online: 10 December 2009
...Jose N. Fernandez del Cotero; Sergio Bonafonte; Aguirre Vila-Coro Central, full-thickness excisional wounds were made in rabbit corneas to evaluate the biomicroscopic changes during the scarring process. Within the first minutes, the wound is closed with a fibrin clot. A timely microscopic study...
Journal Articles
Relationship between Plasma and Tear Fluoride Levels in Rabbit and Man
Available to PurchaseSubject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1990) 22 (1): 39–44.
Published Online: 10 December 2009
...Jarvis T. Chan; Lisa Cheeks; Tracey Slagle; Keith Green Tear fluoride concentrations were determined in rabbits and man. Tear fluoride levels in reflex tears were higher in rabbits (2–10 µmol/l) than in man (1.4–4 µmol/l), while plasma levels were quite similar in both species (1.5–4 µmol/l...
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