..., instructions or products referred to in the content or advertisements. Degeneration Erythropoietin Erythropoietin receptor Hyperoxia Hypoxia Inflammation Neovascularization Permeability Retina Erythropoietin (Epo), a 30.4-kDa glycoprotein hormone, has been identified as a humoral factor...

... endothelial growth factor has been implicated as a major mediator of intraocular neovascularization and permeability. The recent insights into the mechanisms of intraocular angiogenesis have provided new targets for novel nondestructive therapeutic agents directed toward preventing the visual loss associated...

...Keith Green; Tracey Slagle; Manuel J. Chaknis; Lisa Cheeks; Stanley Chang Studies have been made of the effects of intravitreal perfluoro-n-octane on the permeability to fluorescein of the blood-retinal barrier in rabbits. At day 1 after injection, there is increased aqueous humor fluorescence...

... Permeability Fluorophotometer Abstract Corneal autofluorescence and corneal epithelial barrier func­ tion of 146 diabetic patients and 121 controls were examined using anterior segment fluorophotometry. Corneal autofluo­ rescence in diabetic patients was significantly higher when compared with that of controls...

... impaired following 1 h hydrogen peroxide exposure; the cation pump further deteriorated during the subsequent 19-hour incubation. Passive membrane permeability of the lens, measured by 86 Rb efflux, was elevated following 1 h hydrogen peroxide but no further increase in leakiness was observed during...

... perfusion with 125 I-RISA or rabbit serum showed that the permeability characteristics of the blood-aqueous barrier to protein molecules are unaffected in the enucleated eye. The viability of the enucleated eye for secretion of ascorbic acid was also examined, but the results were inconclusive. Arterial...

...C.J.J. Brinkman; R.M. Broekhuyse The experimental radiation cataract in rabbits served as a research model in an investigation of the relation between cataract progression and lens permeability changes. Slit-lamp examination revealed the first lens opacities 12 weeks following X-irradiation...

... eyes, and (5) a striking fall of the level of taurine was noted in the lenticular tissue; it occurred earlier than that of potassium and approximated the levels of the aqueous humor; this change probably also reflects an increased permeability of the membranes rather than a reduction in the transport...

...C.A. Paterson; Beverly A. Eck Prostaglandin E 1 (10 ––3 m) was found to increase sodium and decrease potassium content of the rabbit lens in vitro . 86 Rb uptake and efflux studies demonstrated that both passive permeability and the cation transport mechanism were affected. This study suggests...

... for their efficacy. Methods: We assessed cellular morphology and actin distribution by immunomicroscopy and light microscopy, membrane permeability with transendothelial resistance and cell surface vascular endothelial growth factor receptor-1 (VEGF-R1) expression by flow cytometry. Results: Fludrocortisone acetate...

... permeability when added to solutions bathing the isolated cornea. Inulin/dextran permeability was determined from stromal- to endothelial-facing surfaces of de-epithelialized corneas. The bathing solution was modified Opeguard ® -MA (MOMA), an ocular irrigating solution, to which either GSH or another...