...Bhargavan Chakrapani; Sunita Yedavally; Victor Leverenz; Frank J. Giblin; Venkat N. Ready A sensitive, electrochemical method was employed for the simultaneous measurement of reduced and oxidized glutathione in lens cortex, nucleus and capsule epithelia of rabbit lenses, normal human lenses...

...M.T. Yugay; P.C. Pereira; F. Leiria; M.C. Mota The oxidative effect of hydrogen peroxide, ascorbic acid and glucose in the presence of transition metals was studied. Incubation of bovine lens membranes with hydrogen peroxide/ metal, ascorbic acid/metal and glucose/metal systems resulted...

...P.C. Pereira; R. Fernandes; J.S. Ramalho; M.C. Mota; C.R. Oliveira Oxidative stress has recently been involved in a number of diseases including development of diabetic cataract. If hyperglycemia is the relevant factor in diabetes, then it is reasonable to assume that under physiological conditions...

... of the oxidative metabolism could offer a new approach in the pharmacological modulation of acute corneal inflammation. Original Paper Ophthalmic Res 1993;25:331-336 Jorge L. Alio Maria J. Ayala Emilia Mulet Alberto Artola Juan L. Bellot José M. Ruiz-Moreno Division of Ophthalmology, Laboratory of Ocular...

..., in which the specific activity of SOD was higher than in similar cataracts from nondiabetics. 17 02 1986 29 05 1986 4 12 2009 Superoxide dismutase Oxidation Human lens Cataract Inactive enzymes Immunodetection of enzymes © 1986 S. Karger AG, Basel 1986 Copyright / Drug...

...Hartwig P. Huemer; Markus Nagl; Eveline U. Irschick Objective: Weak oxidants produced by activated human leukocytes are proven antimicrobial substances. We tested whether N-chlorotaurine (NCT, taurine chloramine), the chlorinated metabolite of the amino acid taurine, in addition to direct virucidal...

...Roger J.W. Truscott Age-related nuclear cataract is a major cause of blindness. It is characterised by opacification and colouration in the centre of the lens and is accompanied by extensive protein oxidation. The reason for the onset of nuclear cataract is not known, but it is proposed here...

... by immunocytochemistry/densitometry. These results suggest that many but not all structural and functional parameters of aging Müller cell mitochondria are impaired by accumulating oxidative damage, and that externally applied radical scavengers may protect the organelles from the damaging actions of free radicals...

... OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO Key Words Retina Glia Aging Glutathione Oxidation Free-radical scavengers OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO Abstract The dependence of intracellular glutathione (GSH), an important radical scavenger, on aging with or without externally applied Ginkgo...