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Keywords: Natriuretic peptides
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Journal Articles
Subject Area:
Ophthalmology
Roselie M.H. Diederen, Ellen C. La Heij, Marianne Markerink-van Ittersum, Fred Hendrikse, Jan de Vente
Journal:
Ophthalmic Research
Ophthalmic Res (2008) 40 (5): 227–234.
Published Online: 25 April 2008
... of sGC was further supported by detection of the β 1 - and α 2 -subunits of sGC. Incubation of the cells in the presence of atrial natriuretic peptide (ANP) to stimulate pGC strongly increased cGMP immunoreactivity. We also demonstrated the presence of ANP in all RPE cells. Conclusion: Cultured human RPE...
Journal Articles
Subject Area:
Ophthalmology
Roselie M.H. Diederen, Ellen C. La Heij, Marianne Markerink-van Ittersum, Aize Kijlstra, Fred Hendrikse, Jan de Vente
Journal:
Ophthalmic Research
Ophthalmic Res (2007) 39 (1): 55–59.
Published Online: 15 December 2006
... production. Methods: cGMP expression was evaluated by immunochemistry and radioimmunoassay following culture of the D407 RPE cell line in the presence of a nonselective phosphodiesterase inhibitor (IBMX), in combination with the particulate guanylyl cyclase stimulator atrial natriuretic peptide (ANP...