... days and 7 days after treatment. The levels of inflammatory cytokines (i.e., VEGF, MCP-1, RANTES and IL-6) in the retina/choroid were quantified by an ELISA. The expression patterns of VEGF and macrophages (i.e., F4/80) in the retina/choroid were evaluated by immunohistochemistry. Results: The levels...

...Miao-li Lin; Yong-ping Li; Zhan-rong Li; Jian-xian Lin; Xiao-lai Zhou; Dan Liang Purpose: Our aim was to establish a rat model of proliferative vitreoretinopathy (PVR) induced by macrophages and investigate whether macrophages can be a cell origin of fibroblast-like cells present in PVR. Methods...

...Shibo Tang; Otto F. Scheiffarth †; Stephan R. Thurau; Gerhild Wildner In the present study, we specifically investigated the presence of the main immune cells, namely T helper/inducer lymphocytes, T suppressor/cytotoxic lymphocytes, B lymphocytes and macrophages, for HLA-DR antigen expression...

...Janice M. Burke; Stanley J. Foster The injection of 1.1-μm latex particles into the rabbit vitreous elicits an intravitral invasion of macrophages. The particle-filled macrophages are initially restricted to the vitreous, are later found at the vitreoretinal interface, and by 6 weeks...