...Takako Ueda; Toshihiko Ueda; Donald Armstrong Lipid peroxidation was initiated with 5 m M ferric iron and aliquots of bovine or porcine retina, purified rod outer segments (ROS) and retinal pigment epithelium (RPE). After 30 min of oxidation, the lipid hydroperoxide content of the tissues increased...

...Alberto Artola; Jorge L. Alió; Juan L. Bellot; José M. Ruiz Free radicals, especially the hydroxyl radical (OH • ), are known to be toxic for several ocular structures including the cornea, lens, iris and retina through the initiation of lipid peroxidation of cell membranes. The oxidative damage...

... Glutathione peroxidase Lens-induced uveitis Lipid peroxidation Abstract. An acute lens-induced necrotizing intraocular inflammation was produced in Lewis rats. Treatment of these animals by intraperitoneal injection of glutathione peroxidase resulted in marked decrease in uveal inflammation, retinal edema...

...T.A. Ivanina; N.L. Sakina; M.N. Lebedeva; V.L. Borovyagin The influence of chloroquine on lipid peroxidation in rat and rabbit retinas has been studied. Chloroquine retinopathy is not followed by an increase in lipid peroxidation, and the antioxidant ionol does not prevent the drug effect...

..., and Departments of Ophthalmology and Pathology, and in stitu te for Toxicology, University of Southern California School of Medicine, Los Angeles, Calif., USA Key Words. S antigen Uveitis Lipid peroxidation Vitamin E Arachidonic acid Abstract. The anti-inflammatory effects of vitamin E were investigated...

...Tadahisa Hiramitsu; Donald Armstrong Lipid peroxidation was induced with porcine retinal homogenates using ferric iron or UV light. A number of lipid and aqueous-soluble antioxidants were tested and their protective effects measured after 60 min of exposure. The iron system produced up to 5 times...

... are at present being tested in lens culture and in animal models. Cataract Lens Oxygen radicals Lipid peroxidation © 1988 S. Karger AG, Basel 1988 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced...

...M. Doly; P. Braquet; B. Bonhomme; G. Meyniel The effects of membrane lipid peroxidation are determined in isolated albino rat retina. Lipoperoxidation induced by addition of Fe 2+ + ascorbate to the perfusion liquid leads to an irreversible decrease of amplitude in the electroretinogram...

... on corneal endothelial cells suggest that much of this damage is mediated by free radicals. In this study, we compare the possible effects against lipid peroxidation in the retina of three different viscoelastic substances: Viscoat, Healon and Visiol. Herein we demonstrate for the first time...

... infiltration into the corneal stroma, apoptosis of keratocytes, and suppression of lipid peroxidation of cellular walls. The PRK procedure was performed on both eyes of 10 white rabbits. One eye of each rabbit (the experimental eye) was instilled with the AMO and the other eye of the rabbit (the control eye...

...M. Dolores Pinazo-Durán; Cristina Verdejo; Inmaculada Azorín; Jaime Renau-Piqueras; Francisco J. Iborra Epidemiological and experimental studies suggest the involvement of lipid peroxidation (LPO) in retinal diseases. Clinicians usually prescribe antioxidants to help in the treatment...

...M. Chida; K. Suzuki; T. Nakanishi-Ueda; T. Ueda; H. Yasuhara; R. Koide; D. Armstrong Lipid peroxidation in aliquots of bovine retina (without rod outer segments, ROS), purified ROS and retinal pigment epithelium (RPE) was initiated with 5 m M ferric iron and 80 m M ADP. After 30 min of oxidation...