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Keywords: Lens
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Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1996) 28 (5): 270–274.
Published Online: 11 December 2009
...Masami Oguni; Hiroki Otani; Haruo Shinohara; Kanefusa Kato; Tomoichi Setogawa The localization of 28-kD heat shock protein (HSP28) in the lenses of human embryos (Carnegie stages 13-21) was studied immunohistochemically using antibodies for HSP28. At stage 13, HSP28 was observed in the lens placode...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1996) 28 (5): 275–283.
Published Online: 11 December 2009
..., would account for the high lens fluorescence levels detected in human diabetic cataracts [27, 33], It is however nowclear that most of the fluorophores found in human lenses including pentosidine may orig­ inate efficiently from glucose, fructose and even ascorbate by a sequence of transitionmetal...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1997) 29 (6): 421–428.
Published Online: 11 December 2009
... which have been found to occur in vivo, significantly reducing the chaperone­ like activity of a-crystallin. A comparative decline in chaperone-like activity of a-crystallin was observed in aged a-crystallin isolated from senile human lenses [ 17, 25], It has been suggested that a-crystallin along...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1996) 28 (Suppl. 2): 64–71.
Published Online: 11 December 2009
..., Milton RC, Srivastave S. Ansari N, the Lens Opacities Case-Control Study Group: Biochemical factors in the lens opacities case-control study. Arch Ophthalmol 1995:113:11 131119. 5 Shui YB, Kojima M, Hockwin O, Sasaki K: In vivo morphological changes in rat lenses induced by the administration...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1996) 28 (Suppl. 2): 78–85.
Published Online: 11 December 2009
... during this breakdown of the stores arc accommodated by other cytoplasmic stores. In a recent cytochemical study by Vrensen et al. [5] it was shown that in rat lenses the limiting mem­ branes of lens fibers arc able to bind consider­ able amounts of calcium. The present cytochemical investigation aimed...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1996) 28 (Suppl. 2): 1–4.
Published Online: 11 December 2009
...:421 424. 6 Hendrickson Ph. Robert Y: Con­ trast transfer ratio in normal, cataractous. and intraocular implant lenses: A clinical photopapillometric study. Graefes Arch Clin Exp Oph­ thalmol 1986;224:191-194. 7 Robert Y, Hendrickson Ph: Pho­ tometry of the optic disc; in Lambrou GN. Greve EL (eds...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1996) 28 (Suppl. 2): 109–114.
Published Online: 11 December 2009
.... However, mRNA levels for calpain I in whole lens appeared to be lower compared to calpain-II mRNA. Participation of calpain I in crystallin precipitation during normal maturation of rodent lenses or cataract formation is thus theoretically possible, but unlikely, because of the low level of expression...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1996) 28 (Suppl. 2): 136–140.
Published Online: 11 December 2009
... was found in the nucleus, followed by the deeper anterior and deeper posterior cortices, the shallow anterior and shallow posterior cortices, and the equatorial region. The topographic α-Toc. distribution in the lens did not differ between lenses of 1-, 4- and 12-month-old rats. A significant decrease of α...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1996) 28 (Suppl. 2): 45–53.
Published Online: 11 December 2009
...John L. Hess; Kenneth P. Mitton; G.E. Bunce Selenite treatment of the preweanling rat stabilized the transparency of the lens nucleus to decreasing temperature. Hence, we compared properties of the cortex and nucleus from lenses of selenite-treated and age-matched control rats. A subcutaneous dose...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1995) 27 (Suppl. 1): 13–17.
Published Online: 11 December 2009
... of glutathione in the lens hy Arnold [1] in 19101911. Evidence for glutathione biosynthesis had been achieved in cultured lenses as well as syn­ thesis of an analogue, ophthalmic acid, in lens homogenates [2, 3], However, stepwise synthe­ sis of glutathione and pathways for its catabo­ lism and involvement...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1995) 27 (Suppl. 1): 44–53.
Published Online: 11 December 2009
...H. Rink; A.A. El-Layeh; J. Bours; M.H. Emarah Cataractous lenses from an extended population of 100 Egyptian patients whose age, sex and case history had been recorded, were collected and classified morphologically. After determination of the lens wet weights, lenses were microsectioned and basic...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1995) 27 (Suppl. 1): 54–61.
Published Online: 11 December 2009
... of cataractous lenses were compared with each other, with those of sclerotic lenses and with a normal lens profile. The alterations in the composition of high-molecular-weight (HMW)-, α-, β H -, β L -, β S -, and γ-crystallins along with normal aging, are superimposed by pronounced cataract-related changes which...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1995) 27 (Suppl. 1): 20–24.
Published Online: 11 December 2009
... mittels Lincar-Dcnsitomctrie von Scheimpflug-Photographicn. Fortschr Ophthalmol 1985:82:374 376. 7 Olbert D, Baumgärtner A. Hockwin O, Wahl P, Hasslacher Ch: Follow-up o f lenses o f diabetics by means of linear densitometry of Scheimpflug photos. Lens Res 1986;3:217-225. 8 Olbert D, Ilockwin O...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1995) 27 (Suppl. 1): 143–149.
Published Online: 11 December 2009
... related to age. Curr Eye Res 1983:2:735 742. 34 Rogers KM. Augustyn RC: Glutathi­ one reductase in normal and cataractous human lenses. Exp Eye Res 1978:27:719-721. 35 Reddan JR, Giblin FJ, Dziedzie AC, McCready JP, Reddy VN: Influence o f age on the ability of lens epithelia to detoxify H;0 ;. J Cell...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1995) 27 (Suppl. 1): 78–85.
Published Online: 11 December 2009
... Lens Fiber Membranes Fig. 3. A Dark-field image o f an extracted donor lens exhibiting the small peripheral opac­ ities common in lenses of donors over the age o f 40. The framed area of A shows in SEM that these opacities are parts o f a group o f fibers surrounded by abnormal globular membranes seg­...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1995) 27 (Suppl. 1): 25–33.
Published Online: 11 December 2009
...Masami Kojima; Ying Bo Shui; Kazuyuki Sasaki Topographic distribution of prednisolone in the lens after organ culture was investigated. Freshly enucleated pig lenses were divided into two groups; the complete vitreous was removed from the lenses in group A, and the adherent parts of the vitreous...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1996) 28 (Suppl. 1): 101–104.
Published Online: 11 December 2009
... of Biochemistry of Macromolecules, and c Research Center on Computational Sciences, 2nd University of Naples, Italy Key Words Cataractogenesis Phospholipids Fatty acids Membrane Lens Fatty Acid Composition of Membrane Phospholipids of Cataractous Human Lenses Abstract The effect of lipid peroxidation on fatty...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1996) 28 (Suppl. 1): 55–57.
Published Online: 11 December 2009
...Paul S. Wallace; Susan V. Duff; Alan R. Prescott; Dennis Goebel; Harry Maisel; Roy A. Quinlan The lens-specific intermediate filament (IF) proteins CP49 and filensin have been identified in a large number of evolutionary divergent species. In the chick lens both CP49 and filensin have been...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1996) 28 (Suppl. 1): 97–100.
Published Online: 11 December 2009
... to the amino groups of the lens proteins, is supposed to be one of the causes for cataract develop­ ment through the Maillard reaction [1]. Ly­ sine seems to be the most probable target ami­ no acid for this reaction [2]. In vivo and in vitro studies on cataractous lenses from animals and humans led...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (1996) 28 (Suppl. 1): 69–72.
Published Online: 11 December 2009
...E.J.A. Lea Age-related lens opacity is the major cause of loss of vision affecting more than half of the world’s blind. The development of cataract is associated with changes in the structure of the lens. The lens consists largely of closely packed fibre cells forming a transparent syncytium...