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1-20 of 22
Keywords: Intravitreal injection
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Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (2023) 66 (1): 777–790.
Published Online: 27 March 2023
... in the analysis. Anti-vascular endothelial growth factor agent Diabetic retinopathy Small gauge vitrectomy Intravitreal injection Surgical outcome Proliferative diabetic retinopathy (PDR) is a disease characterized by retinal ischemia, recurrent retinal neovascularization, and fibrous...
Journal Articles
Journal:
Ophthalmic Research
Ophthalmic Res (2023) 66 (1): 653–663.
Published Online: 10 January 2023
...Peter K. Kaiser; Andrea Giani; Holger Fuchs; Victor Chong; Jeffery S. Heier Intravitreal injections of anti-vascular endothelial growth factor (VEGF) agents are used to treat wet age-related macular degeneration (wAMD); however, they are associated with a considerable treatment burden and poor real...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (2022) 65 (3): 287–292.
Published Online: 16 December 2020
... was conducted. Forty patients (40 eyes) received intravitreal injection of ganciclovir (IVG). The aqueous levels of the cytomegalovirus (CMV) DNA and IL-8 in each follow-up visit were tested. The initial and final best-corrected visual acuity (BCVA), the course of treatment, the recurrence rate...
Journal Articles
Subject Area:
Ophthalmology
Audrey Cougnard-Grégoire, Jean-François Korobelnik, Marie-Noëlle Delyfer, Vincent Rigalleau, Vincent Daien, Catherine Creuzot-Garcher, Cécile Delcourt
Journal:
Ophthalmic Research
Ophthalmic Res (2020) 63 (5): 452–459.
Published Online: 25 August 2020
... of optical coherence tomography examinations increased steadily and markedly from 2.7% to 16.2%, while the use of fluorescein and indocyanine green angiographies decreased from 2.4% to 0.9%. In the same period, the yearly rate of intravitreal injection increased from 0.3% to 1.5%, and the use of laser...
Journal Articles
Subretinal Injection: A Review on the Novel Route of Therapeutic Delivery for Vitreoretinal Diseases
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (2017) 58 (4): 217–226.
Published Online: 01 September 2017
...Yingqian Peng; Luosheng Tang; Yedi Zhou Compared to intravitreal injection, subretinal injection has more direct effects on the targeting cells in the subretinal space, which provides a new therapeutic method for vitreoretinal diseases, especially when gene therapy and/or cell therapy is involved...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (2016) 56 (1): 49–55.
Published Online: 09 April 2016
... to break Bruch's membrane. One week later, each rat was intravitreally injected with 5 µl of 15 mg/ml chrysin, and CNV development was determined by fluorescein angiography at 2 weeks. The effect of chrysin on experimental CNV was assessed by fluorescein angiography and histology. Results: Two weeks after...
Journal Articles
Subject Area:
Ophthalmology
Andrew A. Chang, Geoffrey K. Broadhead, Thomas Hong, Nichole Joachim, Adil Syed, Timothy E. Schlub, Levente Toth, Tunde Peto, Meidong Zhu
Journal:
Ophthalmic Research
Ophthalmic Res (2016) 55 (2): 84–90.
Published Online: 05 December 2015
...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 3 09 2015 7 09 2015 5 12 2015 [email protected] Intravitreal injection Neovascular age...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (2015) 53 (1): 15–20.
Published Online: 29 November 2014
...Abdelrahman G. Salman; Aza M. Said Purpose: To study the structural, visual and refractive outcomes of intravitreal injection of aflibercept monotherapy in patients with high-risk prethreshold type 1 retinopathy of prematurity (ROP). Design: Prospective nonrandomized interventional case series...
Journal Articles
Journal:
Ophthalmic Research
Ophthalmic Res (2014) 52 (3): 160–164.
Published Online: 18 October 2014
... persistent SRF, suggesting the anti-inflammatory role of this drug. Intravitreal injection Triamcinolone acetonide Scleral buckling Subretinal fluid Visual acuity Optical coherence tomography Fig. 3 Week 12 OCT of a patient in group 1 (cases). The photoreceptor layer seems to be intact...
Journal Articles
Subject Area:
Ophthalmology
Rony C. Preti, Lisa M.V. Ramirez, Sergio L.G. Pimentel, Yoshitaka Nakashima, Cleide G. Machado, David E. Pelayes, Mario L.R. Monteiro, Walter Y. Takahashi
Journal:
Ophthalmic Research
Ophthalmic Res (2014) 51 (3): 140–145.
Published Online: 08 February 2014
... caused by CRVO characteristically recurs after an initially successful treatment, and many authors have suggested the use of multiple intravitreal injections to improve VA [ 10,13,22 ]. However, it is important to know what to expect during the first treatment for macular thickness (FT and macular volume...
Journal Articles
Subject Area:
Ophthalmology
Carlos Eduardo dos Reis Veloso, Luciana Negrão Frota de Almeida, Franco Maria Recchia, David Pelayes, Márcio Bittar Nehemy
Journal:
Ophthalmic Research
Ophthalmic Res (2013) 51 (1): 1–8.
Published Online: 22 October 2013
...: A total of 92 patients were genotyped for the VEGF rs1413711 single nucleotide polymorphism. Patients with neovascular AMD initially received 3 monthly ranibizumab intravitreal injections and were retreated as needed. Visual acuity (VA) and central retinal thickness (CRT) were measured before and 1, 3, 6...
Journal Articles
Subject Area:
Ophthalmology
Hiroyuki Sakai, Kiyofumi Mochizuki, Makoto Torisaki, Yohko Yamashita, Masaki Komatsu, Toshiro Tanahashi
Journal:
Ophthalmic Research
Ophthalmic Res (1994) 26 (6): 344–351.
Published Online: 11 December 2009
... and histologically. Therefore, the retinal toxicity of ofloxacin is low and within safe limits at clinical dosage. Intravitreal injection Vitrectomy Ofloxacin Endophthalmitis Electroretinogram © 1994 S. Karger AG, Basel 1994 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1993) 25 (2): 128–136.
Published Online: 11 December 2009
... of flomoxef sodium in the vitreous body was undetectable ( < 0.1 μg/ml) in nonvitrectomized eyes. Retinal toxicity of flomoxef sodium was investigated with ophthalmoscopy, electroretinography (ERG) and light microscopy after intravitreal injection of 200, 500, 1,000 and 2,000 μg flomoxef sodium in albino...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1992) 24 (3): 150–154.
Published Online: 10 December 2009
... in the aqueous humor and the vitreous body of normal eyes and in the serum of albino rabbits 3, 6, 12, 24 and 48 h after intravitreal injection of 200 µg. The intravitreal ceftazidime concentration after intravitreal injection decreased exponentially for 12 h (half-life about 7.4 h). It decreased more slowly...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1972) 3 (1): 38–45.
Published Online: 09 December 2009
... Ascorbic acid Vitreous Rabbit Vitamin C Intravitreal injection Hyaluronic acid – depolymerization of Ophthal. Res. 3; 38-45 (1972) Concentration of Amino Acids in the Vitreous after Intravitreal Injection of Ascorbic Acid L. Welge-Lussen and K.P.Schimmel University Eye Clinic, Marburg/Lahn...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1981) 13 (1): 50–59.
Published Online: 04 December 2009
... stabilizes at a reduced level. A concomitant decrease in γ-crystallin synthesis, however, does not occur. Intravitreal injection of 3 H-leucine indicates that the in vivo synthetic rate for α-crystallin is comparable to that found over the initial 18 h in vitro. 22 02 1980 2 06 1980 4 12 2009...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1985) 17 (5): 279–281.
Published Online: 04 December 2009
...J. Morawiecki; R.G. Geursen 22 Rh-positive patients suffering from vitreous hemorrhage caused by injuries to the eye, hypertension, or associated with subarachnoid hemorrhage, were treated with anti-Rh-immunoglobulin by intravitreal injection. 8 patients (36.4%) needed only one immunoglobulin...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1975) 7 (4): 225–235.
Published Online: 03 December 2009
...P. Gruber Rabbits receiving intravitreal injections of 1 mg of horseradish peroxidase reacted with severe uveitis. Specific antibodies against horseradish peroxidase were found in choroidal plasma cells by ultrastructural cytochemical methods at 12,17 and 21 days after intravitreal injection...
Journal Articles
Subject Area:
Ophthalmology
S. Camelo, L. Lajavardi, A. Bochot, B. Goldenberg, M.C. Naud, E. Fattal, F. Behar-Cohen, Y. de Kozak
Journal:
Ophthalmic Research
Ophthalmic Res (2008) 40 (3-4): 145–150.
Published Online: 18 April 2008
... their bioavailability and may induce a sustained release, thus avoiding repeated intraocular injections and reducing side effects. We describe here the fate of rhodamine-conjugated liposomes (Rh-Lip) injected into the vitreous of normal Lewis rats. Twenty-four hours after intravitreal injection fluorescent liposomes...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (2004) 36 (3): 139–144.
Published Online: 23 April 2004
... into four equal groups (10 rabbits in each) and the right eyes were treated with 0.1 ml intravitreal injections of 1,000 µg piperacillin/tazobactam in group 1, 500 µg in group 2, 250 µg in group 3, and 100 µg in group 4. The left eyes served as controls and were injected with 0.1 ml of saline solution...
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