...B. Worgul; H. Rothstein; R. Van Buskirk Uncomplicated perforating injury of frog nictitating membrane evokes a marked migration of cellular elements.It appears most striking in anterior epithelium but occurs also in the posterior layer. One week after injury the wound is partially filled...

...H. Rothstein; B.V. Worgul When frogs were exposed to cold temperature (4°C) the number of mitotic figures in the lens epithelium was reduced by 80–100%. However, mitotic activity does not vary directly with temperature. It is likely that other factors, such as hormones, also regulate proliferation...

...J.R. Reddan; C.V. Harding; H. Rothstein; M.W. Crotty; P. Lee; N. Freeman Rabbit and frog lens epithelial cells can be induced to undergo DNA synthesis and mitosis in a completely defined insulin containing medium. The hormone was added to Medium 199 in these experiments. In general, the insulin...

...D.M. Rosenbaum; H. Rothstein (1) This account presents the results of a series of studies on variations in the mitotic index of frog lens epithelium.(2) Seasonal variations in mitotic index have been found in the lenses of R.catesbeiana and R.pipiens . Though the numbers of division figures vary...

...H. Meissl; S.R. George Extracellular recordings were performed on electrophysiologically identified achromatic neurons of the photosensitive pineal organ of the frog. The effects of iontophoretically applied aspartate and glutamate as well as one aspartate antagonist ( D -α-aminoadipate) were...

...H. Rothstein; B.V. Worgul; C. Medvedovsky, Jr.; George R. Merriam Exposure of the eyes of young frogs and rats to X-rays (12–25 Gy) causes posterior cataracts to appear several weeks later. Hypophysectomized frogs do not develop these opacities, but hypophysectomized rats do. In the former...

...B.V. Worgul; H. Rothstein X-irradiation of frog eyes with natural and experimentally induced differences in lenticular mitotic activity reveals cataractogenesis to be dependent on the proliferative activity of the germinative zone of the lens epithelium. It has also been found that G₀ cells...

...H. Rothstein; R. Van Buskirk; J. Reddan The experiments reported herein prove that wound-associated hyperplasia of frog lenses is inhibited after hypophysectomy. Proliferation can be restored by replacement therapy with either frog pituitary powder or bovine somatotropin. When this is done...