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1-16 of 16
Keywords: Free radicals
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Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (2010) 44 (3): 191–198.
Published Online: 09 September 2010
.... The aetiology of these conditions is thought to fit with the ‘free radical theory’ of ageing which postulates that ageing and age-related diseases result from the accumulation of cellular damage from reactive oxygen species (ROS). Mitochondrial energy production is a major source of endogenous ROS. External...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1995) 27 (2): 102–109.
Published Online: 11 December 2009
...Marta E. Szabo; Marie T. Droy-Lefaix; Michel Doly We studied the effects of a free-radical scavenger, EGb 761 on electrolyte shifts (Na + , Ca 2+ , and K + ) induced by ischemia and reperfusion in the retinas obtained from streptozotocin-induced diabetic rats. Eyes were subjected to 90 min ischemia...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1995) 27 (3): 136–143.
Published Online: 11 December 2009
... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Antioxidants Cornea Corneal scarring Free radicals Inflammation Original Paper Ophthalmic Res 1995;27:136-143 J.L. Alio M.J. Ayala M.E. Mulet...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1993) 25 (3): 172–176.
Published Online: 11 December 2009
...Alberto Artola; Jorge L. Alió; Juan L. Bellot; José M. Ruiz Free radicals, especially the hydroxyl radical (OH • ), are known to be toxic for several ocular structures including the cornea, lens, iris and retina through the initiation of lipid peroxidation of cell membranes. The oxidative damage...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1993) 25 (5): 331–336.
Published Online: 11 December 2009
... measurement of free-radical release, and computer-assisted planimetry of the corneal ulcer and its infiltrate were performed both ex vivo and in vivo on the fifth day following the induction of experimental alkali burn keratitis. The authors proved that both drugs significantly inhibited LAC both ex vivo...
Journal Articles
Subject Area:
Ophthalmology
George E. Marak, Jr., Yvonne De Kozak, Jean-Pierre Faure, Narsing A. Rao, Jorge L. Romero, Peter A. Ward, Gerd O. Till
Journal:
Ophthalmic Research
Ophthalmic Res (1988) 20 (4): 220–226.
Published Online: 10 December 2009
... to in the content or advertisements. Adenosine Free radicals Toxic oxygen metabolites Superoxide Neutrophils Uveitis Experimental allergic uveitis Ophthalmic Res. 20: 220-226 (1988) Pharmacologic Modulation of Acute Ocular Inflammation I. Adenosine1 George E. Marak, Jr.3; Yvonne de Kozakb, Jean...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1989) 21 (3): 230–234.
Published Online: 10 December 2009
.... The role that the high concentration of antioxidants found in the eye may play in modulating acute inflammation is discussed. Antioxidants Free radicals Glutathione peroxidase Superoxide dismutase Uveitis 18 05 1988 12 10 1988 10 12 2009 © 1989 S. Karger AG, Basel 1989...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1993) 25 (1): 1–9.
Published Online: 10 December 2009
...Maria E. Szabo; Marie T. Droy-Lefaix; Michel Doly; Pierre Braquet We investigated the contribution of scavenging of oxygen free radicals to retinal ion contents during ischemia and reperfusion with the use of super-oxide dismutase (SOD, Sigma), allopurinol (Sigma), EGB 761 (extract of Ginkgo biloba...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1989) 21 (2): 112–117.
Published Online: 10 December 2009
... Quercetin Antioxidant Free radicals Cataract Chemotaxis Retinitis Ocular inflammation Ophthalmie Res 1989;21:112-117 Pharmacologic Modulation of Acute Ocular Inflammation with Quercetin Jorge Romero*, George E. Marak, Jr.b, NarsingA. Raoa aDoheny Eye Institute, Departments o f Ophthalmology...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1991) 23 (4): 225–234.
Published Online: 10 December 2009
... of reperfusion resulted in a development of retinal edema in the inner plexiform layer and a migration of neturophils into the retinal tissue. Oxygen free radicals have been implicated as inducers of cell damage in different tissues. This finding has led us to speculate that, if oxygen free radicals play...
Journal Articles
Subject Area:
Ophthalmology
Narsing A. Rao, Mary Ann Fernandez, Alex Sevanian, Jorge L. Romero, Gerd O. Till, George E. Marak Jr
Journal:
Ophthalmic Research
Ophthalmic Res (1988) 20 (2): 106–111.
Published Online: 09 December 2009
... Antiphlogistic agents Free radicals Lens-induced uveitis Ophthalmie Res. 20: 106-111 (1988) Treatment of Experimental Lens-Induced Uveitis by Dimethyl Thiourea NarsingA. Raoa, Mary Ann Fernandeza , Alex Sevanianb, Jorge L. Romeroa , Gerd O. Till0, George E. Marak, Jr.d Estelle Doheny Eye Foundation...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1986) 18 (3): 185–191.
Published Online: 04 December 2009
...Narsing A. Rao; Mary Ann. S Fernandez; Alex Sevanian; Gerd O. Till; George E. Marak, Jr. Oxygen-derived free radicals generated by polymorphonuclear leukocytes have recently been implicated as important pathogenic mediators of tissue damage in immune complex-mediated acute inflammatory reactions...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1986) 18 (4): 193–198.
Published Online: 04 December 2009
... sulfoxide Free radicals Antioxidants Superoxide dismutase Catalase Abstract. Experimental lens-induced uveitis was produced in Lewis rats by sensitization with bovine lens protein prior to disruption of the lens capsule. Treatment of these animals by intraperitoneal injection of dimethyl sulfoxide...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1987) 19 (2): 120–128.
Published Online: 04 December 2009
.... Antioxidants Aspirin Free radicals Nonsteroidal anti-inflammatory drugs Phacoanaphylactic endophthalmitis Prostaglandins Uveitis Ophthalmie Res. 19: 120-128 (1987) Modulation of Experimental Phacoanaphylactic Endophthalmitis with the Antioxidants Sodium Benzoate, and 2,3-Dihydroxybenzoic Acid1 George...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (1983) 15 (6): 324–333.
Published Online: 04 December 2009
...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. X-ray Cataract Mice Galactose Slit lamp Scanning electron microscopy Delay of cataract Free radicals Ophthalmic...
Journal Articles
Subject Area:
Ophthalmology
Journal:
Ophthalmic Research
Ophthalmic Res (2002) 34 (6): 338–342.
Published Online: 23 December 2002
... of hypoxia on bovine retinal pigmented epithelial cells (RPE) and the response of these cells to two antioxidants that have previously shown a beneficial action against free radical-linked senescent involution. The main results of the study were as follows: (i) Hypoxia induced apoptotic damage on RPE cells...