... of ultrawide field (UWF) imaging, and cerebrovascular disease in patients with diabetes mellitus (DM) with different stages of diabetic retinopathy (DR). Methods: 516 eyes of 258 DM patients were enrolled in two centers (Milan and Belfast). UWF color fundus photos (CFPs) were obtained with Optos California...

... of 113 patients with unilateral NAION attack were included and divided into two groups according to whether fellow eye involvement was present over a mean follow-up period of 2.70 years (P25–P75: 0.77–3.54 years). General characteristics (including age, sex, diabetes, hypertension, hyperlipidemia...

...Audrey Cougnard-Grégoire; Jean-François Korobelnik; Marie-Noëlle Delyfer; Vincent Rigalleau; Vincent Daien; Catherine Creuzot-Garcher; Cécile Delcourt Purpose: To describe the use of eye care services among adults treated for diabetes from 2008 to 2017 in the French population. Methods: We used...

...Yu Wang; Zhong Lin; Gang Zhai; Xiao Xia Ding; Liang Wen; Dong Li; Bo Zou; Ke Mi Feng; Yuan Bo Liang; Cong Xie Purpose: The aim of this study was to compare the prevalence of diabetic retinopathy (DR) and diabetic macular edema (DME), as well as their risk factors in patients with early-onset...

...Maria Fernanda Abalem; Helen Nazareth Santos Veloso; Rafael Garcia; Xing Dong Chen; Pedro C. Carricondo; Leandro Cabral Zacharias; Rony C. Preti Objective: The purpose of this study was to evaluate the influence of renal and glycemic parameters on choroidal thickness (CT) in patients with diabetes...

...Conceição Lobo; Isabel Pires; Dalila Alves; Rajeev Pappuru; Luísa Ribeiro; José Cunha-Vaz Purpose: The aim of this study was to examine the relationship between subclinical diabetic macular edema (SCME) and the development of central-involved macular edema (CIME) in patients with diabetes mellitus...

...Luísa Ribeiro; Rajeev Pappuru; Conceição Lobo; Dalila Alves; José Cunha-Vaz Purpose: To evaluate diabetic retinopathy (DR) progression in patients with diabetes mellitus type 2 in 2 populations of different ethnicity. Methods: A prospective observational study was designed to follow eyes/patients...

...João Figueira; José Henriques; Miguel Amaro; Vítor Rosas; Dalila Alves; José Cunha-Vaz Purpose: The aim of this study was to assess the effectiveness and safety of ILUVIEN® in patients with chronic diabetic macular edema (DME) who were insufficiently responsive to prior therapies. Methods...

...; Catarina Neves; Torcato Santos; Luisa Ribeiro; Francesco Bandello; Amparo Navea Tejerina; José Cunha-Vaz; for the EVICR.net Purpose: To characterize the relevance of macular thickness changes in the inner and outer rings in the progression of macular edema in eyes/patients with diabetes type 2. Methods...

...; Frank G. Holz; Sandrina Nunes; Dalila Alves; Catarina Neves; Torcato Santos; Luisa Ribeiro; José Cunha-Vaz; for the EVICR.net Purpose: To identify the retinal layer predominantly affected in eyes with subclinical and clinical macular edema in diabetes type 2. Methods: A cohort of 194 type 2 diabetic...

... Nunes; Dalila Alves; Catarina Neves; Torcato Santos; Luisa Ribeiro; Francesco Bandello; José Cunha-Vaz; for EVICR.net Purpose: To characterize the 1-year progression of retinal thickness (RT) increase occurring in eyes with subclinical macular edema in type 2 diabetes. Methods: Forty-eight type 2...

...Mariacristina Parravano; Francesco Oddone; Barbara Boccassini; Marco Centofanti; Lucia Tanga; Andrea Cacciamani; Patrizia Borboni; Monica Varano Purpose: To investigate functional and morphological retinal changes in the long-term follow-up in subjects with type 1 diabetes mellitus (DM1) without...

...Raimondo Forte; Gilda Cennamo; Maria Luisa Finelli; Paola Bonavolontà; Giovanni Maria Greco; Giuseppe de Crecchio Aim: To evaluate the prevalence, progression and functional predictive value of retinal micropseudocysts (MPCs) in diabetic patients. Methods: Prospective controlled observational study...

...Naim Terai; Eberhard Spoerl; Michael Haustein; Karin Hornykewycz; Janek Haentzschel; Lutz E. Pillunat Background: To investigate the effect of diabetes on the biomechanical behavior of the optic nerve head (ONH) and the peripapillary sclera (ppSc) in streptozocine-induced diabetic rats. Methods...

... injury in individuals with diabetes. We explored associations between variants of the ADORA 2A gene and proliferative diabetic retinopathy (PDR) in a cohort of patients with type 1 diabetes (T1D). Methods: The participants were from the Pittsburgh Epidemiology of Diabetes Complications prospective study...

...Marta E. Szabo; Marie T. Droy-Lefaix; Michel Doly We studied the effects of a free-radical scavenger, EGb 761 on electrolyte shifts (Na + , Ca 2+ , and K + ) induced by ischemia and reperfusion in the retinas obtained from streptozotocin-induced diabetic rats. Eyes were subjected to 90 min ischemia...

...Daniel Meller; Albert J. Augustin; Frank H.J. Koch In this article, the development and application of a modified technique of impression cytology for the electron-microscopic examination of corneal epithelium is presented. Corneal epithelium of controls and diabetic patients was obtained using...

...Hiroyuki Sakai; Yoshie Tani; Eiichi Shirasawa; Yutaka Shirao; Kazuo Kawasaki Development of electroretinographic alterations in 9-week-old experimental diabetic rats was studied for up to 6 weeks after a single intraperitoneal injection of streptozotocin (STZ, 60 mg/ kg). The amplitudes...

... consistently significantly associated with all forms of cataract: diabetes and raised plasma glucose (not in non-diabetics), use of steroid medication, raised levels of cortisol (steroid users excluded), albumin, alkaline phosphatase, γ-glutamyl transpeptidase, sodium and total protein and reduced levels...

...P.C. Pereira; R. Fernandes; J.S. Ramalho; M.C. Mota; C.R. Oliveira Oxidative stress has recently been involved in a number of diseases including development of diabetic cataract. If hyperglycemia is the relevant factor in diabetes, then it is reasonable to assume that under physiological conditions...