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Keywords: Defensin
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Journal Articles

Human Corneal Epithelial Cells Produce Antimicrobial Peptides LL-37 and β-Defensins in Response to Heat-Killed Candida albicans

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Subject Area:
Ophthalmology
Xia Hua, Xiaoyong Yuan, Xin Tang, Zhijie Li, Stephen C. Pflugfelder, De-Quan Li
Journal: Ophthalmic Research
Ophthalmic Res (2014) 51 (4): 179–186.
https://doi.org/10.1159/000357977
Published Online: 18 March 2014
...Xia Hua; Xiaoyong Yuan; Xin Tang; Zhijie Li; Stephen C. Pflugfelder; De-Quan Li Aims: To explore the innate response of human corneal epithelial cells (HCECs) exposed to fungus by producing antimicrobial peptides LL-37 and β-defensins. Methods: Primary HCECs were treated with heat-killed Candida...
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Journal Articles

The Role of Antimicrobial Peptides at the Ocular Surface

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Subject Area:
Ophthalmology
Alison M. McDermott
Journal: Ophthalmic Research
Ophthalmic Res (2009) 41 (2): 60–75.
https://doi.org/10.1159/000187622
Published Online: 20 December 2008
...Alison M. McDermott Antimicrobial peptides (AMPs) such as defensins and cathelicidins are small peptides with broad-spectrum activity against bacteria, fungi and viruses. In addition, several AMPs modulate mammalian cell behaviours including migration, proliferation and cytokine production...
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