... or noninfectious triggers [1, 2]. Noninfectious uveitis entities are related to an aberrant autoimmune or autoinflammatory response [2, 3]. Immunosuppressive treatments such as corticosteroids and immunomodulatory agents have been the mainstay of therapy for noninfectious uveitis [4]. To prevent visual impairment...

... the standard of care for decades, a substantial group of patients are unresponsive and fail to improve after laser treatment. Recently, new pharmacological approaches based on the use of intravitreal drugs, such as corticosteroids and anti-vascular endothelial growth factor, have revolutionized the treatment...

... and biodegradable devices are the most commonly used and approved approaches to deliver various agents to the vitreous. Because of their broad and potent effects, corticosteroids (CS) have been the first-line candidates for intraocular delivery. An increasing spectrum of CS preparations including nondegradable...

... various aspects of drug toxicity in retinal pharmacotherapy. The different major classes of drugs, such as corticosteroids, antibiotics, antimetabolites, antineoplastic agents, monoclonal antibodies (mAbs), nonsteroidal anti-inflammatory drugs, enzymes, fibrinolytics, miscellaneous anti-inflammatory...

...C. Laria; J.L. Alió; J.-M. Ruiz-Moreno Purpose: The effects of anti-inflammatory non-steroidal therapy combined with free-radical scavengers were studied and compared to corticosteroid use in the treatment of experimental corneal injury. Method: Eighty New Zealand albino rabbits were used...

... %) and independent of the number of anti-rejection treatments administered. 22 05 1987 6 01 1988 10 12 2009 Fluorophotometry Lens Lens transmission Autofluorescence Renal disease Non-invasive measuring technique Ultraviolet Aging Corticosteroids © 1988 S. Karger AG, Basel 1988...

...L. Krejčí; H. Krejčová Tissue culture methods were used to study the combined effects of topical corticosteroids and various antiglaucoma drugs on normal corneal epithelium. The results indicate significantly reduced resistance of cultured epithelial cells to a combination of corticosteroids...

...J. François; V. Victoria-Troncoso; P.C. Maudgal; A. Victoria-Ihler; H. Uvijls The corticosteroids may influence the ocular pressure by decreasing the transport by pinocytosis and the formation of transcellular canals in the goniocytes. There may also be an accumulation of hyaluronic acid due...

... with uveitis. Methods: Retrospective study of patients suffering from chronic noninfectious uveitis in whom CME (n = 97) did not respond to systemic corticosteroids and/or immunosuppression combined with acetazolamide. Patients received a single injection of either IVTA (n = 48, group 1) or OFTA (n = 49, group...

... are focused on sustained-release corticosteroids. For neovascular age-related macular degeneration, frequent intravitreal injections of anti-vascular endothelial growth factor compounds are the standard of care. Unmet needs in this population are therapies that reduce the treatment burden and improve visual...

... was more effective than TA in restoring quiescent morphology and reducing membrane permeability in phorbol-12-myristate-acetate (PMA)-stimulated choroidal endothelial cells (CECs). Each of the corticosteroids inhibited VEGF-R1 cell surface expression in PMA-responsive CECs. Conclusion: Mineralocorticoids...

...Yoriko Hayasaka; Seiji Hayasaka; Xue-Yun Zhang; Yasunori Nagaki We evaluated the effects of anti-inflammatory potency of corticosteroids and nonsteroidal anti-inflammatory drugs on prostaglandin E 2 (PGE 2 )-induced aqueous flare elevation in pigmented rabbits. Transcorneal diffusion of PGE 2 , 25...

..., instructions or products referred to in the content or advertisements. Corticosteroids Endotoxin-induced uveitis Intravital microscopy Leukocyte-endothelium interaction Thalidomide Original Paper Ophthalmic Res 2001;33:256 263 Received: December 20, 2000 Accepted after revision: April 11, 2001...

... Anti-inflammatory therapy Corticosteroids Propolis Original Paper Ophthalmic Res 2000;32:13 18 Received: August 14, 1998 Accepted after revision: May 4, 1999 The Effect of Propolis Extract in Experimental Chemical Corneal Injury Faruk Öztürka Emin Kurta Mehmet Çerçib Levent Emirog lua Übeyt I...