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Keywords: Cornea
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Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (2020) 63 (4): 369–374.
Published Online: 21 July 2020
... the possibilities related to the concurrent development of these disorders and the clinical significance for the clinician. Methods: NLM/PubMed, Ovid, Google Scholar, Cornea, and Cochrane database were reviewed for research papers presenting cases of comorbid KC and FD published between January 1990 and July 2019...
Journal Articles
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (2021) 64 (2): 178–191.
Published Online: 29 May 2020
...Ho Lam Wong; Stephanie Hiu Ling Poon; Yashan Bu; Amy Cheuk Yin Lo; Vishal Jhanji; Yau Kei Chan; Kendrick Co Shih Introduction: This review aims to summarise the role of different cells, genes, proteins and lipid in regulating cornea epithelial-stromal homeostasis. Methods: We performed an Entrez...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (2020) 63 (2): 203–212.
Published Online: 06 November 2019
..., analyzing epithelial wound closure, deposits and stromal haze, was carried out at the different study times. Results: No toxic effect was observed by PRGF in hen stromal cell cultures. Clinically, in PRGF-ICRS corneas at 7 days, there were more deposits with higher intensity than in ICRS group...
Journal Articles
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (2019) 62 (3): 141–149.
Published Online: 21 May 2019
...Wenjing Song; Yun Tang; Jing Qiao; Haili Li; Bei Rong; Songlin Yang; Yuan Wu; Xiaoming Yan Background: Genipin (GP) is a safe method for corneal crosslinking, even for very thin corneas. However, there have been no reports on the optimal GP concentration range to use in vivo for corneal...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (2019) 61 (4): 204–209.
Published Online: 22 November 2018
... evaluated how storage in optimized organ culture (OC) medium at 37°C or phosphate-buffered saline (PBS) at 2–8°C impacted physical properties of bovine corneas. Tissue hydration, permeability and histology were monitored at baseline and following 1, 4 and 7 days of storage. Corneas stored in OC demonstrated...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (2018) 60 (2): 80–86.
Published Online: 08 June 2018
.... Dry eye Cornea Refractive surgery Ocular surface Growth factors Laser-assisted in situ keratomileusis (LASIK) is an ophthalmological procedure used to correct refractive errors; in the United States, approximately 650,000 LASIK surgeries are performed each year [ 1 ]. It involves...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (2019) 61 (1): 51–59.
Published Online: 07 April 2018
... study identified significant microstructural alterations in the corneas of eyes treated with topical A/G therapy. In addition, our study also revealed that glaucoma patients treated with topical A/G therapy report significantly higher OSDI scores compared to controls. Thus, IVCM may be a useful tool...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (2014) 52 (4): 170–174.
Published Online: 21 October 2014
... neovascularization and whether the efficacy depends on the route of administration. Materials and Methods: Thirty-six rats were randomly divided into 6 groups with 6 rats in each group. Chemical cauterization of the cornea was performed using silver nitrate/potassium nitrate sticks, and the rats were subsequently...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (2014) 52 (3): 151–159.
Published Online: 08 October 2014
... and resident cells, additional studies are needed to further elucidate their roles in health and disease. The corneal endothelium is a single layer of postmitotic cells arranged in a hexagonal array at the posterior side of the cornea (fig. 1 ). By eliciting osmotically coupled fluid flow from the stroma...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (2014) 51 (2): 82–87.
Published Online: 07 December 2013
... study Cornea Persistent epithelial defect Autologous serum Therapy Wound healing Corneal ulcers and persistent epithelial defects (PEDs) are caused by a variety of insults to the cornea including limbal epithelial stem cell failure [ 1 ]. Healing of an ulcer and PED occurs by corneal...
Journal Articles
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (2013) 50 (3): 135–140.
Published Online: 10 August 2013
...Thomas Ritter; Mieszko Wilk; Mikhail Nosov Cornea transplantation (penetrating keratoplasty) is the most frequently performed transplant procedure in humans. Despite advances in microsurgery and immunosuppressive treatment protocols, a significant number of corneal grafts still undergo immune...
Journal Articles
Ophthalmic Res (2013) 50 (2): 129–133.
Published Online: 08 August 2013
...Eitan Livny; Tami Livnat; Maxim Yakimov; Muhannad Masoud; Dov Weinberger; Irit Bahar Background/Aim: Corneal epithelial defects may heal slowly in patients with diabetes, limbal stem cell deficiency, extensive chemical burns or anesthetized corneas. Studies have shown that erythropoietin...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (2013) 49 (4): 199–204.
Published Online: 10 January 2013
... of astigmatism was performed in the test animals. The cornea is subjected to traumas and injury processes due to its highly exposed location. Among corneal injuries, abrasions, ulcers, lacerations and perforations are the most relevant lesions [ 1 ]. Whether iatrogenic, traumatic, or due to infection...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (2012) 48 (3): 124–133.
Published Online: 09 May 2012
... assay on human corneal epithelial and endothelial cell (EC) lines and on primary human corneal fibroblasts. Paired porcine corneas stored in OC for 3 days were assigned for 48 h to a poloxamine medium or to a standard deswelling medium containing 5% dextran T500. Corneal EC density, morphometry...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (2012) 48 (2): 82–88.
Published Online: 03 April 2012
... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Bone marrow mesenchymal stem cells Coculture Cornea Limbal epithelial cells Paracrine effects Bone marrow...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (2012) 48 (1): 50–55.
Published Online: 02 March 2012
...Resmi A. Charalel; Kristin Engberg; Jaan Noolandi; Jennifer R. Cochran; Curtis Frank; Christopher N. Ta Aims: To determine the rate of diffusion of myoglobin and bovine serum albumin (BSA) through the human cornea. These small proteins have hydrodynamic diameters of approximately 4.4 and 7.2 nm...
Journal Articles
Subject Area:
Ophthalmology
Ophthalmic Res (2012) 48 (1): 22–27.
Published Online: 03 January 2012
...-CT. Conclusions: Our data demonstrate that native corneal epithelial and endothelial cells express a functional 5-HT7 receptor positively coupled to adenylyl cyclase and PKA formation. However, at the present time, the physiological role of 5-HT receptors and the cAMP-PKA pathway in the cornea...