... channels Electrophysiology Calcium Cornea Inflammation Fibrosis Wound healing Temperature-sensitive transient receptor potential channels (thermo-TRPs) are a superfamily which is subdivided into 7 groups according to differences in amino acid sequence homology. Specifically, TRPs...

... the swelling of wild-type Müller cells but not of cells from P2Y 1 R -/- , A 1 AR -/- and IP 3 R2 -/- animals. Conclusion: The swelling-inhibitory effects of VEGF and glutamate in murine Müller cells is mediated by transactivation of P2Y 1 R and A 1 AR, as well as by intracellular calcium signaling via...

...Gijs F.J.M. Vrensen; Anneke de Wolf The distribution of calcium in the human eye lens was investigated using the oxalate-pyroantimonate technique. In epithelial cells and superficial cortical fibers calcium is sequestered and tightly bound to proteins in the endoplasmic reticulum, nuclear envelope...

... been used for immunohisto-chemical investigations of both normal epithelial cell cytoskeletal structure, and of structural changes induced by increasing cell calcium. A sustained increase in intracellular calcium, induced by incubation with A23187 and W7, led to a loss of cytoskeletal organisation...

...Mitsuyoshi Azuma; Larry L. David; Thomas R. Shearer The purpose of this experiment was to determine the contribution of calpain proteolytic enzyme (EC 3.4.22.17) in the formation of nuclear cataract during lens culture in xylose. Increased lens calcium was found to be required for formation...

...Herman Rink; Hermann Twenhöven Calcium content was measured in five different parts of clear bovine lenses obtained from animals throughout the bovine life span of 0.3–24 years. In lenses of animals older than 6 years there is a moderate increase in calcium content with the most significant...

...N.A. Delamere; C.A. Paterson Net changes in the levels of lens calcium, magnesium, sodium, potassium, and water content were determined following exposure in vitro to iodoacetate, ouabain, lanthanum, cyanide, quercetin and cold temperature. The lens calcium content rose following inhibition of lens...

...John I. Clark; Elizabeth Danford We studied lens opacification of rabbit lenses in culture. Opacification was produced by maintaining rabbit lenses in medium containing calcium concentrations as high as 10 mmol/l and the opacity was measured using LASER spectroscopy. Increasing calcium caused...

...H. Rink; J. Münnighoff; O. Hockwin The concentrations of Na + , K + and calcium as well as the water content in whole bovine lenses from 0.25 up to 0 25 years were determined. The data given in μmol/total lens or in μmol/g lens water show a linear increase with ageing for K + , Na + and Ca ++ ions...

...Péter Ràcz; Miklós Kellermayer Calcium, potassium and sodium concentration in normal and senile cataractous lenses was investigated in the course of a long-term dialysis. It was found that about 20% of the calcium content in normal lenses could not be dialysed, whereas in completely opaque lenses...

... of the calcium from the cornea. A further significant decrease of the calcium level was achieved by the action of hydrophilic gel contact lens presoaked with a 1.85% ethylenediamine tetra acetate (EDTA) solution. The lime-burned cornea does not prevent intraocular penetration of EDTA from contact lens fitted...

...H. Rink; J. Münnighoff; O. Hockwin The electrolyte content in whole bovine lenses as well as in the cortical and nuclear regions was determined in a longitudinal study. K + , Na + and calcium contents show distinct age-dependent variations. The total of the 3 cations, the K + /Na + ratio...

..., and guanine prove to be specific inhibitors of this activation. Their mode of action point at calcium as a primary stimulus and phosphoribosylpyrophosphate as a second substance involved in the activating mechanism. Bovine lens epithelium Growth control Cell flattening C 6 -substituted purines Calcium...

...T. Murata; Yoko Taura In calf lenses, cow lenses and human senile cataractous lenses, the contents of iron, copper, zinc, magnesium and calcium were analyzed by the atomic absorption spectrophotometry. Bovine lenses showed regional variations in the elementary contents, in that the zinc and iron...

... without DHT treatment. Rabbit Cornea Calcification Dihydrotachosterol Corneal edema Transport-phenomena Calcium Aqueous humour © 1970 S. Karger AG, Basel 1970 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other...

...M.V. Riley; Mary J. Voaden Species differences in the response of retinal respiration and aerobic glycolysis in vitro to changing levels of calcium and potassium have been detected. In particular omitting calcium from a Krebs-Ringer bicarbonate or phosphate buffer stimulates respiration...

...Moazez J. Marian; Partha Mukhopadhyay; Douglas Borchman; Christopher A. Paterson The plasma membrane calcium ATPase (PMCA) pump is the major mechanism by which calcium is removed from the lens. The aim of this study was to determine if mRNA and proteins levels of PMCA isoforms changed with age...

... and the pyknotic nuclear remnants have disappeared. They are not present in deeper fibres. Our experiments show that intercellular bagels do not stain positive for DNA or RNAs, but are rich in lipids. Preliminary data indicate that the intercellular bagels contain calcium, suggesting that they might act as a place...

...Madeleine Andersson; Johan Sjöstrand; Anne Petersen; Jan-Olof Karlsson The purpose of this study was to examine changes in calcium-dependent proteolytic activity in the lens epithelium from whole rabbit lenses exposed to long-term oxidative stress at near physiological levels. Rabbit lenses...

...Osman Cekic; Yavuz Bardak Lenticular calcium (Ca), magnesium (Mg), and iron (Fe) changes in diabetic rats and the effects of the Ca antagonist drug verapamil on this electrolyte imbalance were studied. Verapamil administration had no effect on the blood glucose values. Compared to the control group...