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Keywords: Benzalkonium chloride
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Journal Articles

Hyperosmolarity and Benzalkonium Chloride Differently Stimulate Inflammatory Markers in Conjunctiva-Derived Epithelial Cells in vitro

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Subject Area:
Ophthalmology
Elise Warcoin, Chloé Clouzeau, Christophe Roubeix, Anne-Laure Raveu, David Godefroy, Luisa Riancho, Christophe Baudouin, Françoise Brignole-Baudouin
Journal: Ophthalmic Research
Ophthalmic Res (2017) 58 (1): 40–48.
https://doi.org/10.1159/000448117
Published Online: 10 December 2016
...Elise Warcoin; Chloé Clouzeau; Christophe Roubeix; Anne-Laure Raveu; David Godefroy; Luisa Riancho; Christophe Baudouin; Françoise Brignole-Baudouin Tear hyperosmolarity is known to cause ocular surface inflammation in dry eye syndrome. Benzalkonium chloride (BAK), an eyedrop preservative, is known...
View articletitled, Hyperosmolarity and Benzalkonium Chloride Differently Stimulate Inflammatory Markers in Conjunctiva-Derived Epithelial Cells in vitro
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Journal Articles

Corneal Penetration into Rabbit Aqueous Humor Is Comparable between Preserved and Preservative-Free Tafluprost

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Subject Area:
Ophthalmology
Pertti Pellinen, Jukka Lokkila
Journal: Ophthalmic Research
Ophthalmic Res (2009) 41 (2): 118–122.
https://doi.org/10.1159/000192082
Published Online: 16 January 2009
...Pertti Pellinen; Jukka Lokkila Background: Some studies have shown that benzalkonium chloride (BAK), a preservative used in antiglaucoma medications, can increase corneal permeability by acting as a penetration enhancer. Tafluprost is a new prostaglandin F 2 α analog in clinical use...
View articletitled, Corneal Penetration into Rabbit Aqueous Humor Is Comparable between Preserved and Preservative-Free Tafluprost
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Journal Articles

Very-High-Frequency Ultrasound Corneal Imaging as a New Tool for Early Diagnosis of Ocular Surface Toxicity in Rabbits Treated with a Preserved Glaucoma Drug

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Subject Area:
Ophthalmology
Alexandre Denoyer, Frederic Ossant, Brigitte Arbeille, Franck Fetissof, Frederic Patat, Léandre Pourcelot, Pierre-Jean Pisella
Journal: Ophthalmic Research
Ophthalmic Res (2008) 40 (6): 298–308.
https://doi.org/10.1159/000134928
Published Online: 28 May 2008
... to a benzalkonium-chloride-containing antiglaucoma drug. Methods: Timolol preserved with 0.01% benzalkonium chloride solution was applied b.i.d. in 1 eye of 10 rabbits for 56 days. Unpreserved timolol solution was used as control. Ocular surface changes were assessed weekly combining clinical examinations, in vivo...
View articletitled, Very-High-Frequency Ultrasound Corneal Imaging as a New Tool for Early Diagnosis of Ocular Surface Toxicity in Rabbits Treated with a Preserved Glaucoma Drug
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Journal Articles

Acute Corneal Epithelial Change after Instillation of Benzalkonium Chloride Evaluated Using a Newly Developed in vivo Corneal Transepithelial Electric Resistance Measurement Method

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Subject Area:
Ophthalmology
Masafumi Uematsu, Takeshi Kumagami, Mao Kusano, Koki Yamada, Kazuaki Mishima, Koichi Fujimura, Hitoshi Sasaki, Takashi Kitaoka
Journal: Ophthalmic Research
Ophthalmic Res (2007) 39 (6): 308–314.
https://doi.org/10.1159/000109986
Published Online: 22 October 2007
...Masafumi Uematsu; Takeshi Kumagami; Mao Kusano; Koki Yamada; Kazuaki Mishima; Koichi Fujimura; Hitoshi Sasaki; Takashi Kitaoka Objective: Acute corneal permeability change after instillation of benzalkonium chloride (BAC) was evaluated using a newly developed in vivo corneal transepithelial...
View articletitled, Acute Corneal Epithelial Change after Instillation of Benzalkonium Chloride Evaluated Using a Newly Developed in vivo Corneal Transepithelial Electric Resistance Measurement Method
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