... Xu Department of Ophthalmology, First People s Hospital of Shanghai Affiliated to Shanghai Jiaotong University, Shanghai, China Key Words Diabetic retinopathy Neurodegeneration Oxidative stress Antioxidants Abstract Oxidative stress plays a role in the pathogenesis of neurodegeneration...

...Vaishali Agte; Kirtan Tarwadi Background: The lens is the ocular structure most susceptible to oxidative damage. Antioxidants, micronutrients and phytochemicals have been extensively studied for their possible effects to prevent or delay the progression of various eye diseases. Objectives: A brief...

...J.L. Alio; M.J. Ayala; M.E. Mulet; A. Artola; J.M. Ruiz; J. Bellot To ascertain the effectiveness of topical antioxidant therapy on acute corneal inflammation, we have studied the effectiveness of topical treatment with a saline solution and with antioxidants such as 0.2% superoxide dismutase...

... approximately 4- to 8-fold over control levels with ROS showing the greatest change and RPE the lowest. Eight lipid and aqueous antioxidants from natural or synthetic sources and five flavonoids were evaluated for their ability to inhibit the reaction. Species differences were observed with regard...

... to in the content or advertisements. Trabeculectomy Tenonߣs capsule fibroblasts Cell culture Vitamin E d -α-Tocopherol Antioxidants Ophthalmic, Research Original Paper Ophthalmic Res 1996;28:171-175 Anita L. Haasa Daniel Boscoboinikb Daniels. Mojona Matthias Böhnkea Angelo Azzih 1 University Eye...

...Yvonne de Kozak; Jean-Phillip Nordman; Jean-Piere Faure; Narsing A. Rao; George E. Marak, Jr. The antioxidant enzymes superoxide dismutase and glutathione peroxidase have been observed to be effective antiphlogistic agents in severe experimental allergic uveitis induced by retinal S antigen in rats...

...Tadahisa Hiramitsu; Donald Armstrong Lipid peroxidation was induced with porcine retinal homogenates using ferric iron or UV light. A number of lipid and aqueous-soluble antioxidants were tested and their protective effects measured after 60 min of exposure. The iron system produced up to 5 times...

...İclal Yücel; Nadir Paksoy; Gültekin Yücel; Güler Aksu; Aslan Aksu In order to assess the role of vitamin E, an antioxidant, in the treatment of uveitis, a controlled experimental study was carried out on 20 New Zealand albino rabbits with bovine-albumin-induced uveitis. In all vitamin-E-treated...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Antioxidants Catalase Glutathione peroxidase Lens-induced uveitis Lipid peroxidation Ophthalmic Res. 20: 213-219...

... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Dimethyl thiourea Antioxidants...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Lens-induced uveitis Dimethyl sulfoxide Free radicals Antioxidants Superoxide dismutase Catalase Original Papers...

...George E. Marak, Jr.; Narsing A. Rao; Alex Sevanian; Vera Zdravkovich; Gerd O. Till; Peter A. Ward The antioxidants sodium benzoate and 2,3-dihydroxybenzoic acid reduced the inflammatory response in experimental phacoanaphylactic endophthalmitis. The 2,3-dihy-droxybenzoic acid was by far the more...

... that melanin production does occur in the adult eye, it seems not improbable that antioxidants (or agents that modify cellular redox status) may have melanin stimulatory (or inhibitory) effects that are superimposible on their effects as mere free radical scavengers. More empirical studies are needed...

... of hypoxia on bovine retinal pigmented epithelial cells (RPE) and the response of these cells to two antioxidants that have previously shown a beneficial action against free radical-linked senescent involution. The main results of the study were as follows: (i) Hypoxia induced apoptotic damage on RPE cells...

...S.K. Gupta; N. Halder; S. Srivastava; D. Trivedi; S. Joshi; S.D. Varma Cataract is the leading cause of blindness worldwide. It is a multifactorial disease primarily associated with oxidative stress produced by free radicals. The protection offered by various antioxidants in cataract development...

... and aqueous antioxidants (AOX) from natural or synthetic sources, including five flavonoids, were evaluated for their ability to inhibit the oxidative reaction. Palm-oil-derived vitamin E showed significant protection in retina, ROS and RPE (64, 68 and 74%), respectively. Of the flavonoids tested, good...