... hypothesized that this difference may be due to alternative splicing of COX-1 mRNA in the human iris or in whole blood. In this study, we have identified a similar COX-1 splice variant (COX-1SV) in both tissues with comparable COX-1/COX-1SV expression ratios. Therefore, we conclude that the difference in IC 50...

... a cDNA that looked the same as the phosducin-like protein of the rat, as reported by other investigators. We examined the gene expression in rat retina using semiquantitative polymerase chain reaction and compared it to that of other organs. One form generated by alternative splicing expressed...