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Keywords: Age-related macular degenerationClose
Ophthalmic Res (2023) 66 (1): 1353–1361.
Published Online: 03 November 2023
...Qingqing Zheng; Ting Shen; Mengyue Xu; Lingtong Tan; Zeqi Shen; Chaoyang Hong Introduction: One of the most common conditions that causes permanent blindness globally is age-related macular degeneration (AMD). The purpose of the present study was to determine the association between vitamin B1...
Ophthalmic Res (2023) 66 (1): 791–800.
Published Online: 12 May 2023
...Luca Cedro; Laura Hoffmann; Katja Hatz Introduction: The aim of this large-scale long-term retrospective study was to show the enlargement rate (ER) of geographic atrophy (GA) in age-related macular degeneration (AMD), defined as complete retinal pigment epithelium and outer retinal atrophy (cRORA...
Ophthalmic Res (2023) 66 (1): 516–528.
Published Online: 23 January 2023
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 CircularRNA Back splicing Retinoblastoma Age-related macular degeneration Diabetic retinopathy With the development of bioinformatics and transcriptomics...
Ophthalmic Res (2023) 66 (1): 406–412.
Published Online: 25 November 2022
...Yi Guo; Jinye Wu; Xueying Zheng; Chang Yin; Zhenyu Wu Introduction: Due to its progressive nature, early evaluation and timely prediction of legal blindness are important in patients with neovascular age-related macular degeneration (nAMD). We examined the association between early-stage variation...
Shoji Notomi, Satomi Shiose, Yosuke Fukuda, Kenichiro Mori, Sawako Hashimoto, Kumiko Kano, Keijiro Ishikawa, Koh-Hei Sonoda
Ophthalmic Res (2023) 66 (1): 108–115.
Published Online: 17 August 2022
...Shoji Notomi; Satomi Shiose; Yosuke Fukuda; Kenichiro Mori; Sawako Hashimoto; Kumiko Kano; Keijiro Ishikawa; Koh-Hei Sonoda Introduction: Drusen and pigmentary abnormality are found as the hallmark to predict progression of age-related macular degeneration (AMD). In Asian populations, exudative AMD...
Julián Garcia-Garcia, Ricardo Usategui-Martin, Maria Rosa Sanabria, Esther Fernandez-Perez, Juan Jose Telleria, Rosa M. Coco-Martin
Ophthalmic Res (2022) 65 (6): 615–636.
Published Online: 25 May 2022
...Julián Garcia-Garcia; Ricardo Usategui-Martin; Maria Rosa Sanabria; Esther Fernandez-Perez; Juan Jose Telleria; Rosa M. Coco-Martin Age-related macular degeneration (AMD) is a complex, multifactorial, progressive retinal disease that affects millions of people worldwide and has become the leading...
Ophthalmic Res (2022) 65 (3): 351–360.
Published Online: 02 February 2022
...Lucas Janeschitz-Kriegl; Marco Cattaneo; Hendrik P.N. Scholl Introduction: The accumulation of lipofuscin is a hallmark in the pathogenesis of Stargardt disease type 1 (STGD1) and geographic atrophy (GA) secondary to age-related macular degeneration. Limiting lipofuscin accumulation by inhibiting...
Ophthalmic Res (2022) 65 (3): 245–253.
Published Online: 16 December 2021
... relationship to ocular disease, focusing on autoimmune uveitis, diabetic retinopathy, age-related macular degeneration, and primary-open angle glaucoma. We discuss findings and limitations of this exciting new area of ophthalmology research and explore possible future disease-modifying treatments...
Ophthalmic Res (2022) 65 (2): 140–151.
Published Online: 28 September 2021
...Xue Wang; Chaofeng Yu; Jiasong Yang; Yuzhen Liu; Yali Xu; Wensheng Li Background: Conbercept, as a novel vascular endothelial growth factor (VEGF) inhibitor, was approved for the treatment of neovascular age-related macular degeneration (nAMD) in China. Objective: This study aimed to compare...
Ophthalmic Res (2021) 64 (6): 888–902.
Published Online: 21 June 2021
...Hendrik P.N. Scholl; David Boyer; Andrea Giani; Victor Chong Geographic atrophy (GA) secondary to age-related macular degeneration accounts for close to one-quarter of cases of legal blindness in the USA and the UK. Despite this notable disease burden, the pathophysiology of GA is complex...
Ophthalmic Res (2021) 64 (5): 696–703.
Published Online: 17 February 2021
...Ziming Xu; Mei Zhang; Qing Zhang; Tingjuan Xu; Liming Tao Background: Although epidemiologic studies have suggested that thyroid disease may be a risk factor for age-related macular degeneration (AMD), this finding is still controversial. Objectives: The aim of this meta-analysis was to investigate...
Ophthalmic Res (2021) 64 (5): 704–712.
Published Online: 16 December 2020
...Chang-Xi Chen; Mei-Ling Liu; Kai Cao; Mayinuer Yusufu; Jin-Da Wang Objective: This study aims to evaluate the diagnostic value of optical coherence tomography angiography (OCTA) in detecting the choroidal neovascularization (CNV) in age-related macular degeneration (AMD). Methods: A systematic...
Ophthalmic Res (2021) 64 (3): 369–388.
Published Online: 02 October 2020
...Laura Borchers; Johann Roider; Alexa Klettner Introduction: Anti-VEGF therapy is repeatedly given for an extended period of time to patients when treated for age-related macular degeneration. While short-term effects of anti-VEGF agents on retinal pigment epithelial cells have been investigated...
Ophthalmic Res (2020) 63 (4): 375–382.
Published Online: 21 July 2020
.... The study participants were patients with wet age-related macular degeneration (AMD) in one eye who developed wet AMD in the contralateral eye, with at least 2 years of follow-up prior to conversion. The Moorfields Eye Hospital database was searched for eligible patients and their data were recorded. Eyes...
Constanze Kortuem, Tobias Marx, Elke Karin Altpeter, Susanne Trauzettel-Klosinski, Stephan Kuester-Gruber
Ophthalmic Res (2021) 64 (3): 512–522.
Published Online: 25 June 2020
... to in the content or advertisements. 2020 Reading speed Variability Repeatability Age-related macular degeneration Low vision Maculopathy Sentences Paragraphs To test reading speed (RS) in a clinical and research setting, standardized reading texts are necessary. Such texts are available...
Ophthalmic Res (2021) 64 (2): 192–204.
Published Online: 19 May 2020
...Jun Zhang; Zhaohui Liu; Shuqiong Hu; Jian Qi Age-related macular degeneration (AMD) causes irreversible vision loss, and targeted anti-vascular endothelial growth factor (VEGF) therapy is now the most common and effective treatment. The aim of this meta-analysis is to discuss whether genetic...
João Esteves Leandro, João Beato, Ana Catarina Pedrosa, João Pinheiro-Costa, Manuel Falcão, Fernando Falcão-Reis, Ângela M. Carneiro
Ophthalmic Res (2020) 63 (5): 466–473.
Published Online: 27 January 2020
..., or the use of drugs, and patients are aware of the unreality of these images [ 2, 3 ]. CBS is associated with ocular pathology and visual loss, with the most commonly predisposing disorder being age-related macular degeneration (AMD) [ 4 ]. Other risk factors that have been identified include age, social...
Ophthalmic Res (2020) 63 (5): 460–465.
Published Online: 07 January 2020
... was to determine RTM in growth rate measurements in patients with geographic atrophy (GA) secondary to age-related macular degeneration. Methods: We conducted a retrospective analysis of the GAIN (NCT01694095) and its extension study, in which individuals 50 years or older with pure GA were followed for a minimum...
Ophthalmic Res (2020) 63 (4): 404–412.
Published Online: 20 December 2019
...Renzhe Cui; Lianji Tian; Di Lu; Huiying Li; Jun Cui Aims: Oxidative damage plays a vital role in the pathogenesis of age-related macular degeneration (AMD). Exendin-4 (EX4), a glucagon-like peptide-1 receptor agonist, possesses several pharmacological functions, such as anti-inflammatory...
Ophthalmic Res (2020) 63 (3): 271–283.
Published Online: 30 October 2019
... Multimodal imaging Retinal pigment epithelium Choroidal neovascularization Age-related macular degeneration Laser photocoagulation was performed using a 532-nm argon laser (Visulas Trion; Carl Zeiss, Jena, Germany) in conjunction with a slit-lamp delivery system (Accento; Carl Zeiss). Only 1 eye...