...Marilita M. Moschos; Irini Chatziralli; Anna Sioziou; Maria Gazouli Purpose: The purpose of this study was to investigate the potential association between primary open-angle glaucoma and receptor of advanced glycation end products (AGER) polymorphisms in a Greek population. Methods: This is a case...

... of the earliest features of diabetic retinopathy prior to obvious vascular changes in diabetic retinas. We have previously shown that serum levels of advanced glycation end products (AGEs) are correlated with a delayed latency of OPs in type 2 diabetic rats. However, the pathological role of AGEs in ERG...

... by nonenzymatic collagen cross-linking mediated by advanced glycation end products due to high blood glucose levels in diabetes. Further studies are needed to investigate if these biomechanical changes represent a detrimental risk factor for intraocular pressure regulation in diabetic glaucoma patients. 22...

... of the Maillard Reaction P. Vidal, J. Cabezas-Cerrato Department of Physiopathology, Service of Endocrinology and Nutrition, Hospital General dc Galicia, University of Santiago, Santiago de Compostela, Spain Key Words. Glycation Browning Advanced glycation end products Pig lens crystallins Bovine serum...

...Sho-ichi Yamagishi; Takanori Matsui; Kazuo Nakamura; Hiroyoshi Inoue; Masayoshi Takeuchi; Seiji Ueda; Seiya Okuda; Tsutomu Imaizumi Background/Aims: We have previously shown that interaction between advanced glycation end products (AGEs) and their receptor (RAGE) evokes generation of reactive...

...Sho-ichi Yamagishi; Takanori Matsui; Kazuo Nakamura; Takafumi Yoshida; Masayoshi Takeuchi; Hiroyoshi Inoue; Yumiko Yoshida; Tsutomu Imaizumi The interaction of advanced glycation end products (AGEs) and their receptor (RAGE) elicits inflammatory and proliferative responses in retinal vascular wall...

...Simi Padival; Ram H. Nagaraj Purpose: Advanced glycation end products (AGEs) play an important role in protein modification during cataract formation. Along with sugars, α-dicarbonyl compounds, such as methylglyoxal (MGO), have been implicated in AGE formation. Here we report the effect...

...Chihiro Katsumura; Tetsuya Sugiyama; Kimitoshi Nakamura; Hiroshi Obayashi; Goji Hasegawa; Hidehiro Oku; Tsunehiko Ikeda Purpose: To test the effects of advanced glycation end products (AGEs), which are increased in vitreous of diabetic patients, on photolysis of hyaluronan. Methods: Pullulan...

...) in OLETF rats than in control rats at the age of 60 weeks. Moreover, their retinal mRNA level was positively correlated with serum concentration of advanced glycation end products (AGEs) but not to serum glucose concentration. Furthermore, the peak latency of the oscillatory potentials...