... were included in the meta-analysis. The primary outcome was postoperative mean IOP at the 12-month follow-up. No significant difference in IOP was found between the bevacizumab + antimetabolite (mitomycin c or 5-fluorouracil) group and the antimetabolite alone group (weighted mean difference –0.27; 95...

...Wisam Shihadeh; Ihab Massad; Yousef Khader; Ahmed Al-Rawi; Tala Alshalakhti Purpose: To compare the outcomes of trabeculectomy with 5-fluorouracil (5-FU) versus Ologen™ implant in patients with primary open-angle glaucoma. Methods: A retrospective chart review was performed of patients with primary...

...Friederike Lindemann; Niklas Plange; David Kuerten; Hannah Schimitzek; Antonis Koutsonas Purpose: To evaluate the long-term outcome of trabeculectomy with intra- and postoperative 5-fluorouracil (5-FU) application in glaucoma. Methods: Eighty-six patients with glaucoma planned for primary...

...Mahmoud Mohamed Ismail; Jorge L. Alió; José Mª Ruiz Moreno To prevent the development of secondary cataract, mitomycin C (MC, 0.2 mg/ml) and 5-fluorouracil (5-FU, 50 mg/ml) were introduced in the irrigating solution (BSS Plus) during an extracapsular lens extraction in albino rabbits. Cellular...

...Avinoam Ophir The rate of retinal detachment in fellow control eyes of rabbits following fibroblast administration is progressively lower with increased dose of 5-Fluorouracil in the test eyes. Thus, it seems mandatory to choose control eyes in other animals rather than the fellow eyes...

...J.M. Ruíz; M. Medrano; J.L. Alió An extracapsular cataract extraction was performed on both eyes of 24 rabbits. Irrigation for 10 min of the capsular bag of the left (test) eye with 8–12 cm 3 of 1 litre of BSS-plus® to which had been added 50 mg of 5-fluorouracil significantly inhibited...