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First page of Postoperative outcomes of one-month silicone oil tamponade in rhegmatogenous retinal detachment: a multicenter study

Introduction: To investigate postoperative outcomes in patients who underwent rhegmatogenous retinal detachment (RRD) surgery. Methods: This was a multicenter retrospective study involving 263 patients who underwent silicone oil (SiO) tamponade for RRD. Patients were divided into three groups based on the SiO tamponade: one month (Group 1, n=55), three months (Group 2, n=176), and six months (Group 3, n=32). The main outcomes were best corrected visual acuity (BCVA), intraocular pressure ( IOP), and retinal structure one month after silicone oil removal (SOR). Results: In the analysis of retinal structure in post-SOR, The median central macular thickness (CMT) in Group 1, 2 and 3 were 182.5 μm (IQR: 156.0-214.0), 170.0 μm (IQR: 140.3-211.5), 152.0 μm (IQR: 92.3-195.3), and the median ganglion cell layer-Inner plexiform layer (GCL-IPL) in Group 1, 2 and 3 were 80.5 μm (IQR: 70.0-92.3), 73.0 μm (IQR: 65.0-81.3), 65.0 μm (IQR: 56.3-79.0), respectively. Both CMT and GCL-IPL differ significantly with the Group 1 exhibiting the thickest retinal structure (P = 0.03 and P=0.006). IOP differ significantly across groups, with Group 3 showing the highest IOP in post-SOR (P = 0.015). However, there were no significant differences in BCVA, inner retinal layer thickness (IRLT), outer retinal layer thickness (ORLT), or submacular fluid (SMF) among the groups. Conclusions: Prolonged SiO tamponade is correlated with increased IOP and the thinning of the CMT and GCL-IPL over time, with favorable postoperative outcomes for one-month silicone oil tamponade. Given the potential risks of extended tamponade, it is advisable to remove silicone oil as soon as anatomically feasible.

The Author(s). Published by S. Karger AG, Basel
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2025
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License .
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