20 experimental amelanotic Greene melanomas implanted into the anterior chamber of rabbit eyes were examined immunohistochemically in paraffin sections. All the Greene melanomas were found to be positive for vimentin, S-100 and HMB 45 and negative for α-human chorionic gonadotropin, neuron-specific enolase, chromogranin, synaptophysin, cytokeratin, carcino-embryonic antigen, serotonin, desmin and pan leukocyte marker T-200. Greene melanoma is comparable with human cutaneous and uveal melanoma in its immunohistochemical reaction pattern.

Keywords:
Greene melanoma, Immunohistochemistry, Vimentin, S-100, HMB 45
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© 1992 S. Karger AG, Basel
1992
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